Efficacy Testing of Collagen Peptide Drink

NCT04996043 | Completed

• 1 other identifier: 21-042-B2
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To assess Collagen Peptide Drink on skin condition improvement

Conditions

Skin Condition

Outcome Measures

Primary Outcomes (6)

• The change of skin wrinkles

  VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

  Change from Baseline skin wrinkles at 4 weeks

• The change of skin texture

  VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

  Change from Baseline skin texture at 4 weeks

• The change of skin collagen density

  DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units

  Change from Baseline skin collagen density at 4 weeks

• The change of skin elasticity

  Soft Plus was utilized to measure skin elasticity. Units: arbitrary units

  Change from Baseline skin elasticity at 4 weeks

• The change of MMP-1 of blood

  Venous blood was sampled to measure MMP-1

  Change from Baseline MMP-1 at 4 weeks

• The change of TIMP-1 of blood

  Venous blood was sampled to measure TIMP-1

  Change from Baseline TIMP-1 at 4 weeks

Secondary Outcomes (14)

• The change of skin melanin index

  Change from Baseline skin melanin index at 4 weeks

• The change of skin L* value

  Change from Baseline L* value at 4 weeks

• The change of skin spots

  Change from Baseline skin spots at 4 weeks

• The change of skin UV spots

  Change from Baseline skin UV spots at 4 weeks

• The change of skin brown spots

  Change from Baseline skin brown spots at 4 weeks

Other Outcomes (7)

• The change of total cholesterol of blood

  Change from Baseline total cholesterol at 4 weeks

• The change of triglyceride of blood

  Change from Baseline triglyceride at 4 weeks

• The change of SGOT of blood

  Change from Baseline SGOT at 4 weeks

Study Arms (2)

Placebo drink

PLACEBO COMPARATOR

Dietary Supplement: Placebo drink

Collagen Peptide Drink

EXPERIMENTAL

Dietary Supplement: Collagen Peptide Drink

Interventions

Collagen Peptide Drink DIETARY_SUPPLEMENT

Testing product

Also known as: Pearlosophy-Collagen Peptide Drink

Collagen Peptide Drink

Placebo drink DIETARY_SUPPLEMENT

Blank

Placebo drink

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 20 years old

You may not qualify if:

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
• Constant drug use
• Participated cosmetic product human study in the past 3 months.

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy ＆ Science

Tainan, 71710, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

• Chia-Hua Liang

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 3, 2021
• First Posted: August 9, 2021
• Study Start: May 17, 2021
• Primary Completion: September 28, 2021
• Study Completion: November 25, 2021
• Last Updated: January 5, 2022

Record last verified: 2022-01

Locations

TW (1)