NCT04709588

Brief Summary

Collagen combined with djulis and green caviar improve skin condition

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2020

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 11, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 14, 2021

Completed
Last Updated

January 14, 2021

Status Verified

January 1, 2021

Enrollment Period

2 months

First QC Date

January 11, 2021

Last Update Submit

January 12, 2021

Conditions

Outcome Measures

Primary Outcomes (7)

  • skin moisture

    using corneometer CM825 to examine skin moisture (The higher the value, the more water content, C.U., corneometer units )

    subjects drank 50 ml every night for 28 days

  • skin elasticity

    using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit)

    subjects drank 50 ml every night for 28 days

  • skin gloss

    using probe system GL2000 \& MPA10 to examine skin gloss (The higher the value, the higher the gloss, no unit)

    subjects drank 50 ml every night for 28 days

  • skin spot

    usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2)

    subjects drank 50 ml every night for 28 days

  • skin wrinkle

    using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW)

    subjects drank 50 ml every night for 28 days

  • skin roughness

    using VISIOSCAN-VC98 to examine skin roughness (The higher the value, the higher the roughness, surface evaluation of roughness, SEr)

    subjects drank 50 ml every night for 28 days

  • skin smoothness

    using VISIOSCAN-VC98 to examine skin smoothness (The lower the value, the higher the smoothness, surface evaluation of smoothness, SEsm)

    subjects drank 50 ml every night for 28 days

Study Arms (2)

placebo group

PLACEBO COMPARATOR

subjects drank 50 ml every night for 14, 28 days

Dietary Supplement: placebo group

collagen drinks

EXPERIMENTAL

subjects drank 50 ml every night for 14, 28 days

Dietary Supplement: collagen drinkss

Interventions

placebo groupDIETARY_SUPPLEMENT

subjects drank 50 ml every night for 14, 28 days

placebo group
collagen drinkssDIETARY_SUPPLEMENT

subjects drank 50 ml every night for 14, 28 days

collagen drinks

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Dry skin
  • Rough skin
  • Large pores
  • Dark yellow complexion
  • Sagging skin

You may not qualify if:

  • Skin disorders
  • Liver diseases
  • Kidney diseases
  • Allergy to cosmetics, drugs, or foods
  • Pregnant and lactating women
  • People who had any cosmetic procedures before 4 weeks of the study
  • Area of facial spot over 3 cm2
  • Vegan
  • People who took collagen supplements in the past 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Research & Design Center, TCI CO., Ltd

Taipei, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

  • Chi Fu Chiang, Ph.D

    Research & Design Center, TCI CO., Ltd

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2021

First Posted

January 14, 2021

Study Start

May 1, 2020

Primary Completion

June 30, 2020

Study Completion

August 31, 2020

Last Updated

January 14, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations