Brief Summary

The purpose of this study is to compare the cognitive performance following the ingestion of carbohydrate solutions containing either maple syrup, maple sap, corn syrup, a commercial sport drink or water.

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

participants targeted

Target at P50-P75 for not_applicable

Timeline

Completed

Started Aug 2017

Shorter than P25 for not_applicable

Geographic Reach

1 country

1 active site

Status

completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

8 months study duration

Study Start

First participant enrolled

August 8, 2017

Completed

5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 22, 2017

Completed

3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2018

Completed

1.4 years until next milestone

First Submitted

Initial submission to the registry

August 20, 2019

Completed

21 days until next milestone

First Posted

Study publicly available on registry

September 10, 2019

Completed

Last Updated

September 10, 2019

Status Verified

August 1, 2019

Enrollment Period

5 months

First QC Date

August 20, 2019

Last Update Submit

September 9, 2019

Conditions

Carbohydrate Ingestion Cognitive Performance High Intensity Interval Training

Outcome Measures

Primary Outcomes (4)

Change in Cognitive flexibility
Measured with a computerized version of the 4th board of Stroop's Task.
Baseline (Before the exercise protocol), during the 3-minutes exercise bouts, and every 15 minutes during the 45 minutes following exercise.
Change in Mental Effort
Measured with the DP-15 Scale, ranging from 1 to 15, 1 corresponds to "very, very easy" and 15 is "very, very hard"
Baseline (Before the exercise protocol), during the 3-minutes exercise bouts, and every 15 minutes during the 45 minutes following exercise.
Change in Perceived exertion
Measured using a Category Ratio scale on 10 points (CR10), 0 signifies no exertion and 10 being maximal effort.
Baseline (Before the exercise protocol), during the 3-minutes exercise bouts, and every 15 minutes during the 45 minutes following exercise.
Change in Brain oxygenation
Measured with near-infrared spectroscopy (NIRS).
During Stroop's task (i.e.before the exercise protocol, during the 3-minutes exercise bouts, and every 15 minutes during the 45 minutes following exercise).

Secondary Outcomes (1)

Change in Blood glucose concentration
Baseline (Before the exercise protocol), during the 3-minutes exercise bouts, and every 15 minutes during the 45 minutes following exercise.

Study Arms (5)

Maple Syrup

EXPERIMENTAL

A maple syrup solution of 6% carbohydrate per volume labeled with 13C-sucrose will first be ingested at rest (167 mL), right before starting warmup. Another dose (167 mL) will be administered after warmup. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.

Dietary Supplement: Solution ingestionBehavioral: Cognitive flexibilityProcedure: Brain oxygenationOther: PalatabilityProcedure: Blood glucoseBehavioral: Perceived exertionBehavioral: High Intensity Interval Training bouts

Maple sap

EXPERIMENTAL

A maple sap solution of 6% carbohydrate per volume labeled with 13C-sucrose will first be ingested at rest (167 mL), right before starting warmup. Another dose (167 mL) will be administered after warmup. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.

Glucose

ACTIVE COMPARATOR

A glucose solution of 6% carbohydrate per volume labeled with 13C-sucrose will first be ingested at rest (167 mL), right before starting warmup. Another dose (167 mL) will be administered after warmup. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.

Sports drink

ACTIVE COMPARATOR

A commercial sports drink of 6% carbohydrate per volume labeled with 13C-sucrose will first be ingested at rest (167 mL), right before starting warmup. Another dose (167 mL) will be administered after warmup. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.

Water

PLACEBO COMPARATOR

A solution containing stevia (sugar substitute) labeled with 13C-sucrose will first be ingested at rest (167 mL), right before starting warmup. Another dose (167 mL) will be administered after warmup. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.

Interventions

Solution ingestionDIETARY_SUPPLEMENT

Subjects will be required to ingest 1 liter of the experimental solution, spread over the 45 minutes of exercise. A first ingestion of 167 mL of solution will be made at rest, right before starting warmup, and another dose (167 mL) after it. Four additional doses of 167 mL will be ingested immediately after the first four 3-minute bouts at 95% of Maximal Aerobic Power. A final dose (167 mL) will be ingested after the last effort.