NCT03700671

Brief Summary

High intensity interval training (HIIT) and circuit training (CT) are popular methods of exercise, eliciting improvements in cardiorespiratory fitness (CRF). However direct comparisons of these two training methods are limited.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 11, 2016

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 11, 2017

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 13, 2017

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

October 4, 2018

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 9, 2018

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

February 17, 2020

Completed
Last Updated

February 17, 2020

Status Verified

February 1, 2020

Enrollment Period

1 year

First QC Date

October 4, 2018

Results QC Date

October 10, 2018

Last Update Submit

February 13, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Maximal Oxygen Consumption (ml.Kg-1.Min-1)

    Maximal oxygen consumption (ml.kg-1.min-1), as determined during a cardiopulmonary exercise test (CPET) represents the upper limit of aerobic fitness in humans. A low VO2max is associated with a greater risk of premature all-cause and cardiovascular mortality, independent of traditional risk factors and physical activity status. Conversely, increasing VO2max through exercise training may improve cardiometabolic health, quality of life and increase life-expectancy

    Baseline and 8 weeks

Secondary Outcomes (1)

  • Oxygen Consumption at the Ventilatory Anaerobic Threshold

    Baseline and 8 weeks

Other Outcomes (2)

  • Intervention Fidelity - Participants That Complied With the Exercise Protocols

    8 weeks

  • The Percentage of Individuals That Responsed to the Intervention

    8 weeks

Study Arms (2)

High intensity interval training

EXPERIMENTAL

HIIT was set at \> 85% HRmax. Active recovery was set at 25-50 watts. Sessions were performed using cycle ergometry.

Other: High intensity interval training

Circuit training

ACTIVE COMPARATOR

The CT group completed a practical seven-station mixed modality exercise circuit (cycle ergometer, rower, treadmill, sit to stand, knee to elbow and leg kickback with bicep curl) at an intensity of 60-80%. Participants initially performed 20 minutes of CT with duration gradually increased to the desired 40 minutes as tolerated. Each station was occupied for three to six minutes depending on session duration with minimal rest in-between.

Other: Circuit training

Interventions

Participants performed HIIT twice a week for eight weeks. Findings were compared to moderate intensity continuous training which followed the same exercise frequency and duration

High intensity interval training

The CT group completed a practical seven-station mixed modality exercise circuit (cycle ergometer, rower, treadmill, sit to stand, knee to elbow and leg kickback with bicep curl) at an intensity of 60-80% HRmax twice per week for eight weeks. Participants initially performed 20 minutes of CT with duration gradually increased to the desired 40 minutes as tolerated

Circuit training

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants reported no medical history of cardiometabolic or limiting respiratory disease, were non-smokers, had a body mass index \<30 kg.m-2, classified as recreationally active

You may not qualify if:

  • Cardiometabolic disease, high activity levels, Unable to tolerate the exercise intervention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Univeristy of Hull

Hull, Kingston Upon Hull, HU67RX, United Kingdom

Location

Related Publications (44)

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MeSH Terms

Interventions

High-Intensity Interval TrainingCircuit-Based Exercise

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Results Point of Contact

Title
Stefan Birkett Lecturer in Exercise Science
Organization
University of Central Lancashire

Study Officials

  • Stefan Birkett, PhD

    University of Central Lancashire

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: Participants were randomised to either high or moderate intensity exercise
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer in Exercise Science

Study Record Dates

First Submitted

October 4, 2018

First Posted

October 9, 2018

Study Start

May 11, 2016

Primary Completion

May 11, 2017

Study Completion

December 13, 2017

Last Updated

February 17, 2020

Results First Posted

February 17, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations