Nutritional Deficiencies About Recurrent Miscarriage
Study on Nutritional Deficiencies and Related Factors in Patients With Recurrent Miscarriage
1 other identifier
observational
1,000
1 country
1
Brief Summary
The study plans to recruit patients with recurrent miscarriage and detect their niacin, thiamine, vitamin A, vitamin B6, vitamin B12, vitamin D levels in plasma, evaluating if some lack exists.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2019
CompletedFirst Submitted
Initial submission to the registry
August 20, 2019
CompletedFirst Posted
Study publicly available on registry
August 22, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 12, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2022
CompletedMarch 15, 2022
March 1, 2021
2.3 years
August 20, 2019
March 14, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Plasma niacin levels in the enrolled population.
2019-11 to 2020-1
Secondary Outcomes (2)
plasma thiamine, vitamin A, vitamin B6, vitamin B12, vitamin D levels of the enrolled population
2019-11 to 2020-1
full exon sequence of the enrolled population
2019-11 to 2020-1
Study Arms (3)
recurrent abortion
women of childbearing age who have spontaneous abortion within 20 weeks of pregnancy for 2 or more consecutive times.
normal pregnancy history
Women of childbearing age who had a normal pregnancy history and are not in pregnancy status now.
general population
Women of childbearing age in general examination.
Interventions
Detection of niacin and other vitamins in plasma
Eligibility Criteria
Recurrent abortion population without confirmed diagnosis of known causes
You may qualify if:
- Research group 1: Recurrent abortion group: women of childbearing age who have spontaneous abortion within 20 weeks of pregnancy for 2 or more consecutive times.
- Control group: 1) Women of childbearing age who had a normal pregnancy history and are not in pregnancy status now. 2) Women of childbearing age in general examination.
You may not qualify if:
- patients with confirmed causes unrelated to nutritional deficiencies, including
- Both husband and wife have been diagnosed with chromosomal abnormalities or fetal chorionic chromosomal abnormalities;
- The patient has been diagnosed with uterine abnormalities;
- vaginal bacterial infection or chlamydial infection;
- antiphospholipid antibody syndrome;
- Other immune system diseases (hypothyroidism, PCOS, hyperprolactinemia);
- ovarian function decline (FSH\>10mIU/ml);
- Cervical insufficiency5.3 Exit criteria:
- After being selected, the researcher was withdrawn due to various considerations.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, 100730, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Qi Yu, Professor
Peking Union Medical College Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Months
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 20, 2019
First Posted
August 22, 2019
Study Start
August 1, 2019
Primary Completion
November 12, 2021
Study Completion
November 1, 2022
Last Updated
March 15, 2022
Record last verified: 2021-03