Trials Sponsors Conditions Drugs Pricing

Conditions

Acute Lymphoblastic Leukemia Acute Myelogenous Leukemia Chronic Myelogenous Leukemia Lymphoma Multiple Myeloma Myelodysplastic Syndromes Myeloproliferative Neoplasm

Outcome Measures

Primary Outcomes (1)

Clinical response to treatment
Collect clinical responses to treatment and outcomes in patients who have provided samples to the biobank
3 years

Secondary Outcomes (2)

Type of clinical treatment responses
3 years
Types of somatic tumor mutations
3 years

Study Arms (1)

Single group

Documented hematologic malignancy in need of starting an active anti-cancer therapy. This is a non-interventional study.

Other: This is a non-interventional study

Interventions

This is a non-interventional studyOther

N/A. This is a non-interventional study. Following consent, the subject will have biospecimen samples taken during routine standard of care procedures, and provided to Sponsor for analysis. Optional research blood draws may occur at treating physician's discretion to obtain additional tissue samples.

Single group

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Approximately 1000 Subjects with diagnosed with a hematological malignancy will be enrolled to provide at least 1000 biospecimen samples.

You may qualify if:

Provide written informed consent;

Sponsors & Collaborators

Notable Labs
Industrylead

Study Sites (20)

CBCC Global Research

Bakersfield, California, 93309, United States

Pacific Central Coast Health Centers -- SLO Oncology and Hematology Health Center

San Luis Obispo, California, 93401, United States

Colorado West Healthcare System, dba Grand Valley Oncology

Grand Junction, Colorado, 81505, United States

Ocala Oncology Center

Ocala, Florida, 34474, United States

Mid Florida Hematology and Oncology Center

Orange City, Florida, 32763, United States

Touro Infirmary

New Orleans, Louisiana, 70115, United States

Northern Light Cancer Care Center

Biospecimen

Retention: SAMPLES WITH DNA

The study will require tissue samples taken from consented subjects to be assayed using Notable's ex vivo, high-throughput flow cytometry based platform. The result of this assay will be compared to the subject's documented diagnosis as well as clinical outcome, where applicable. Additional biomarker testing, such as sequencing to determine somatic mutations using targeted panels, may also be conducted.

MeSH Terms

Conditions

Leukemia, Myeloid, AcuteMultiple MyelomaMyelodysplastic SyndromesLymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMyeloproliferative Disorders

Condition Hierarchy (Ancestors)

Leukemia, MyeloidLeukemiaNeoplasms by Histologic TypeNeoplasmsHematologic DiseasesHemic and Lymphatic DiseasesNeoplasms, Plasma CellHemostatic Disorders

Study Officials

Hiroomi Tada, MD, Ph.D.
Notable Labs
PRINCIPAL INVESTIGATOR

Enrollment

119 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: OTHER
Time Perspective: PROSPECTIVE
Target Duration: 1 Year
Sponsor Type: INDUSTRY
Responsible Party: SPONSOR

Study Record Dates

First Submitted

July 3, 2019

First Posted

July 10, 2019

Study Start

December 15, 2019

Actual (reported)

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Single group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (20)

Related Links

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (1)

Single group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (20)

Related Links

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations