Key Insights

Highlights

Success Rate

80% trial completion

Published Results

137 trials with published results (21%)

Research Maturity

277 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.8%

71 terminated out of 660 trials

Success Rate

79.6%

-7.0% vs benchmark

Late-Stage Pipeline

10%

68 trials in Phase 3/4

Results Transparency

49%

137 of 277 completed with results

Key Signals

137 with results80% success71 terminated

Data Visualizations

Phase Distribution

536Total
Not Applicable (69)
Early P 1 (17)
P 1 (189)
P 2 (193)
P 3 (41)
P 4 (27)

Trial Status

Completed277
Recruiting122
Unknown80
Terminated71
Active Not Recruiting59
Not Yet Recruiting22

Trial Success Rate

79.6%

Benchmark: 86.6%

Based on 277 completed trials

Clinical Trials (660)

Showing 20 of 20 trials
NCT05334069RecruitingPrimary

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

NCT07572136Phase 1Recruiting

Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT05621291Not ApplicableRecruiting

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

NCT01494103Phase 1Active Not RecruitingPrimary

Administration of Donor T Cells With the Caspase-9 Suicide Gene

NCT07320534Phase 4Terminated

Levofloxacin Prophylaxis to Prevent First Febrile Neutropenia in Pediatric ALL During Induction Phase

NCT07328503Phase 2RecruitingPrimary

CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

NCT05969002Completed

Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias

NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

NCT03802695Phase 1Recruiting

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

NCT07246213RecruitingPrimary

CAYA Cancer Retrospective Cohort Study

NCT03494569Phase 1SuspendedPrimary

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT06144606Phase 2Recruiting

Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT07295951Phase 1CompletedPrimary

A Study of 14C-Bleximenib (Radiolabeled) in Participants With Acute Leukemia

NCT03779854Phase 2Active Not Recruiting

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

NCT05748171Phase 2RecruitingPrimary

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

NCT06308588Phase 1Recruiting

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

NCT04732845Phase 1Active Not Recruiting

Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies

NCT03226704Enrolling By Invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT02003222Phase 3Active Not RecruitingPrimary

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

NCT04065399Phase 1Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

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