Key Insights

Highlights

Success Rate

80% trial completion

Published Results

60 trials with published results (40%)

Research Maturity

94 completed trials (62% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

15.9%

24 terminated out of 151 trials

Success Rate

79.7%

-6.8% vs benchmark

Late-Stage Pipeline

13%

19 trials in Phase 3/4

Results Transparency

64%

60 of 94 completed with results

Key Signals

60 with results80% success24 terminated

Data Visualizations

Phase Distribution

138Total
Not Applicable (14)
Early P 1 (1)
P 1 (43)
P 2 (61)
P 3 (12)
P 4 (7)

Trial Status

Completed94
Terminated24
Recruiting13
Withdrawn6
Unknown6
Active Not Recruiting4

Trial Success Rate

79.7%

Benchmark: 86.5%

Based on 94 completed trials

Clinical Trials (151)

Showing 20 of 20 trials
NCT04888741Phase 2Recruiting

Methods of T Cell Depletion Trial (MoTD)

NCT07354074Phase 2RecruitingPrimary

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

NCT03578367Phase 2Completed

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Who Have Been Previously Treated With Imatinib and Have Not Achieved Deep Molecular Response.

NCT00816114RecruitingPrimary

Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical Trial

NCT01890486Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

NCT05088356Phase 1Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

NCT07489755Phase 3Not Yet RecruitingPrimary

TGRX-678 Chinese Phase III in Chronic Myelogenous Leukemia (CML) Patients

NCT04948333Phase 3CompletedPrimary

Asciminib Treatment Optimization in ≥ 3rd Line CML-CP

NCT04904588Phase 2Active Not Recruiting

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

NCT01962636Not ApplicableRecruiting

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

NCT01366612Phase 3Terminated

PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation

NCT04877522Phase 4RecruitingPrimary

Asciminib Roll-over Study

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT03674411Phase 2Active Not Recruiting

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

NCT04191187Phase 2Completed

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

NCT02996773Phase 1Completed

Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine

NCT01316250Not ApplicableCompletedPrimary

Gleevec as Maintenance Therapy After Cytogenetic Response With Nilotinib in Newly Diagnosed Chronic Myelogenous Leukemia

NCT01784068Phase 2CompletedPrimary

Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) Patients

NCT01660607Phase 1Completed

Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

NCT01494103Phase 1Active Not Recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene

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