NCT03894930

Brief Summary

The purpose of the study is to look at the impact of a metta meditation training on prosocial behavior and socio-affective brain responses. The training involves an 8-week, online administration of guided metta meditation practices aimed at generating feelings of kindness and compassion for other people. The study examines how participants respond to thinking about familiar others and strangers using behavioral and brain-imaging measures. This study will be important for understanding how people develop the capacity to be prosocial towards other individuals, which is a key component of adaptive social behavior.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 25, 2018

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

March 27, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 29, 2019

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 14, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 14, 2021

Completed
Last Updated

June 16, 2021

Status Verified

July 1, 2020

Enrollment Period

2.6 years

First QC Date

March 27, 2019

Last Update Submit

June 15, 2021

Conditions

Keywords

healthy subjectsprosocialmetta meditationfMRI

Outcome Measures

Primary Outcomes (2)

  • Social Discounting

    During functional magnetic resonance imaging (fMRI) scanning, participants will complete a social discounting task. Participants will choose whether to forgo various amounts of money to give to another person. Behavioral and brain responses will be analyzed to assess social discounting in each participant.

    8 weeks

  • Affective Brain Responses to Familiar and Unfamiliar Others

    During functional magnetic resonance imaging (fMRI) scanning, participants will view images of people who they know and people who they do not know. Affective brain response patterns will be analyzed to assess responding in each participant.

    8 weeks

Secondary Outcomes (1)

  • State Affect Rating

    8 weeks

Study Arms (2)

Metta meditation

EXPERIMENTAL

Eight-week, guided metta meditation training that is administered online

Behavioral: Metta meditation

Wait-list

NO INTERVENTION

Eight-week wait-list control with no training

Interventions

Administered 5 days per week for 8 weeks.

Also known as: Loving-kindness meditation
Metta meditation

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Is a medically healthy individual
  • Lives in the Washington, D.C. metro area and is able to travel to Georgetown University

You may not qualify if:

  • Has experience with meditation
  • Has any MRI contraindication (e.g. metal in the body, cardiac pacemaker, cannot lie still, etc.)
  • Has any neurological disease
  • Has a current psychiatric disorder
  • Is pregnant or planning to become pregnant
  • Is on medication that affects the central nervous system (e.g. psychotropic drugs)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Georgetown University

Washington D.C., District of Columbia, 20007, United States

Location

MeSH Terms

Conditions

Social Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Abigail A Marsh, PhD

    Georgetown University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 27, 2019

First Posted

March 29, 2019

Study Start

September 25, 2018

Primary Completion

May 14, 2021

Study Completion

May 14, 2021

Last Updated

June 16, 2021

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations