NCT02745431

Brief Summary

The current study aimed to investigate oxytocin effect on the response after the experience of being liked or disliked.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
86

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2015

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

April 15, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 20, 2016

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
Last Updated

August 1, 2017

Status Verified

November 1, 2016

Enrollment Period

1 year

First QC Date

April 15, 2016

Last Update Submit

July 29, 2017

Conditions

Social Behavior

Keywords

LikeabilityBeing liked

Outcome Measures

Primary Outcomes (1)

  • Oxytocin effect on likeability after being liked or disliked

    Likeability rating was included into analysis as dependent factor.

    2 hour

Secondary Outcomes (1)

  • Relationship status may influence oxytocin effect

    2 hour

Study Arms (2)

Oxytocin nasal spray

EXPERIMENTAL

Oxytocin nasal spray

Drug: Oxytocin

Placebo nasal spray

PLACEBO COMPARATOR

Placebo nasal spray

Drug: Placebo

Interventions

OxytocinDRUG
Oxytocin nasal spray
PlaceboDRUG
Placebo nasal spray

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy subjects without past or current psychiatric or neurological disorder

You may not qualify if:

  • history of head injury;
  • claustrophobia;
  • medical or psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Life Science and Technology, University of Electronic Science and Technology

Chengdu, Sichuan, 611731, China

Location

Related Publications (1)

  • Zhao W, Ma X, Le J, Ling A, Xin F, Kou J, Zhang Y, Luo R, Becker B, Kendrick KM. Oxytocin biases men to be more or less tolerant of others' dislike dependent upon their relationship status. Psychoneuroendocrinology. 2018 Feb;88:167-172. doi: 10.1016/j.psyneuen.2017.12.010. Epub 2017 Dec 22.

    PMID: 29304421DERIVED

MeSH Terms

Conditions

Social Behavior

Interventions

Oxytocin

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Pituitary Hormones, PosteriorPituitary HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPeptidesAmino Acids, Peptides, and Proteins

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 15, 2016

First Posted

April 20, 2016

Study Start

June 1, 2015

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

August 1, 2017

Record last verified: 2016-11

Locations

CN(1)