NCT02963194

Brief Summary

To determine whether the neuropeptide oxytocin (OXT) influences self-processing by investigating whether it increases the endowment effect in relation to both self and others.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2015

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 15, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
6 months until next milestone

First Posted

Study publicly available on registry

November 15, 2016

Completed
Last Updated

November 15, 2016

Status Verified

November 1, 2016

Enrollment Period

4 months

First QC Date

April 15, 2016

Last Update Submit

November 9, 2016

Conditions

Social Behavior

Keywords

self-processingendowment effectneuroimage

Outcome Measures

Primary Outcomes (1)

  • Compared the indifference point between buy and sell conditions during the price phase and the specific brain region activation between oxytocin and placebo groups

    Indifference point is the gap between willingness to accept and willingness to pay ;focus on the specfic brain region relasted to self-processing, such as medial prefrontal cortex, precuneus, posterior cingulate cortex, ventral striatum.

    1 hour

Study Arms (2)

Oxytocin

EXPERIMENTAL

Oxytoxin nasal spray

Drug: Oxytocin

Placebo

PLACEBO COMPARATOR

Placebo nasal spray

Drug: Placebo

Interventions

OxytocinDRUG
Oxytocin
PlaceboDRUG
Placebo

Eligibility Criteria

Age18 Years - 27 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy subjects without past or current psychiatric or neurological disorders

You may not qualify if:

  • history of head injury;
  • claustrophobia;
  • medical or psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Life Science and Technology, University of Electronic Science and Technology

Chengdu, Sichuan, 611731, China

Location

MeSH Terms

Conditions

Social Behavior

Interventions

Oxytocin

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Pituitary Hormones, PosteriorPituitary HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPeptidesAmino Acids, Peptides, and Proteins

Study Officials

  • Keith Kendrick, Dr.

    University of Electronic Science and Technology of China

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 15, 2016

First Posted

November 15, 2016

Study Start

November 1, 2015

Primary Completion

March 1, 2016

Study Completion

June 1, 2016

Last Updated

November 15, 2016

Record last verified: 2016-11

Locations

CN(1)