Metastatic Breast Cancer in Austria

NCT03870620 | Recruiting

• 1 other identifier: AGMT_MBC-Registry
• Study Type: observational
• Target: 5,000
• Locations: 1 country
• Sites: 16

Brief Summary

Breast cancer is the most common cancer among women worldwide. In Austria, this diagnosis is made more than 5000 times a year (STATISTICS AUSTRIA, Austrian Cancer Registry, as of 24.09.2012). Of these, already 5% to 10% have distant metastases at the time of initial diagnosis, and up to 30% of the node-negative tumours and up to 70% of the node-positive tumours metastasise at a later date. Metastatic breast cancer has not been systematically assessed in Austria to date. This medical registry of the AGMT is thus the first Austrian-wide standardised documentation of this disease. The aim of the registry is to answer both epidemiological and therapy-specific questions. This registry is a prospective and retrospective, multicentre collection of data on patients with metastatic breast cancer in Austria. All tumour characteristics, medical histories and also treatment sequences are documented in anonymised form.

Conditions

Breast Cancer; Breast Carcinoma; Breast Tumor

Outcome Measures

Primary Outcomes (4)

• Number of patients with prognostic factors for metastatic breast cancer

  10 years

• Number of patients according to molecular subtypes

  10 years

• Frequency and tumour characteristics of breast cancer in male patients

  10 years

• Overall survival of patients with metastatic breast cancer in Austria

  10 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This registry is a prospective and retrospective, multicentre collection of data on patients with metastatic breast cancer in Austria.

You may qualify if:

• Histological evidence of breast cancer
• Histological and/or radiological evidence of metastases
• Metastasis within 10 years of registry initiation
• Signed informed consent (if a patient has already died at the time of entry, the entry can be made without a declaration of consent)

Sponsors & Collaborators

• Arbeitsgemeinschaft medikamentoese Tumortherapie: lead
• Hoffmann-La Roche: collaborator
• Daiichi Sankyo: collaborator
• Pfizer: collaborator
• Novartis: collaborator
• Caris Life Sciences: collaborator
• AstraZeneca: collaborator
• Seagen Inc.: collaborator
• Eli Lilly and Company: collaborator

Study Sites (16)

Landeskrankenhaus Salzburg Universitätsklinikum der Paracelsus Medizinischen Privatuniversität; Universitätsklinik für Innere Medizin III Salzburg

Salzburg, Salzburg, 5020, Austria

RECRUITING

Steiermärkische Krankenanstalten- gesellschaft m. b. H. LKH-Univ. Klinikum Graz; Universitätsklinik für Innere Medizin; Klinische Abteilung für Onkologie

Graz, Styria, 8036, Austria

RECRUITING

Landeskrankenhaus - Universitätskliniken Innsbruck; Universitätsklinik für Frauenheilkunde Innsbruck

Innsbruck, Tyrol, 6020, Austria

RECRUITING

BKH Kufstein; Innere Medizin: Interne II und onk. Tagesklinik

Kufstein, Tyrol, 6330, Austria

RECRUITING

Kepler Universitätsklinikum; Univ.-Klinik für Hämatologie und Internistische Onkologie

Linz, Upper Austria, 4020, Austria

RECRUITING

Ordensklinikum Linz GmbH - Barmherzige Schwestern; Interne I: Medizinische Onkologie und Hämatologie

Linz, Upper Austria, 4020, Austria

RECRUITING

Pyhrn-Eisenwurzen Klinikum Steyr; Innere Medizin II: Onkologie, Gastroenterologie, Angiologie

Steyr, Upper Austria, 4400, Austria

RECRUITING

Klinikum Wels-Grieskirchen GmbH; Abteilung für Innere Medizin IV

Wels, Upper Austria, 4600, Austria

RECRUITING

AKH Wien; Universitätsklinik für Frauenheilkunde: Klin. Abt. f. Allg. Gynäkologie und gynäkologische Onkologie

Vienna, Vienna, 1090, Austria

RECRUITING

LKH Feldkirch; Innere Medizin II/ Interne E (Hämatologie und Onkologie)

Feldkirch, Vorarlberg, 6800, Austria

RECRUITING

Krankenhaus St. Josef Braunau; Inneren Medizin 2

Braunau am Inn, 5280, Austria

RECRUITING

Krankenhaus der Stadt Dornbirn; Brustgesundheitszentrum Dornbirn

Dornbirn, 6850, Austria

RECRUITING

Steiermärkische Krankenanstalten- gesellschaft m.b.H. LKH Hochsteiermark; Department für Hämato-Onkologie

Leoben, 8700, Austria

RECRUITING

Universitätsklinikum St. Pölten; Abteilung für Innere Medizin 1

Sankt Pölten, 3100, Austria

RECRUITING

UK AKH Wien: Universitätsklinik für Innere Medizin I: Klinische Abteilung für Onkologie

Vienna, 1090, Austria

RECRUITING

Klinik Ottakring; 1. Med. Abteilung, Zentrum f. Onkologie, Hämatologie und Palliativmedizin

Vienna, 1160, Austria

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Richard Greil, MD

  AGMT gemeinnützige GmbH

  STUDY CHAIR

Central Study Contacts

Daniela Wolkersdorfer

CONTACT

+43 662 6404412; d.wolkersdorfer@agmt.at

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 8, 2019
• First Posted: March 12, 2019
• Study Start: June 15, 2015
• Primary Completion: June 1, 2025
• Study Completion: June 1, 2025
• Last Updated: April 10, 2025

Record last verified: 2025-04

Locations

AU (16)