Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

26.9%

46 terminated/withdrawn out of 171 trials

Success Rate

65.7%

-20.9% vs industry average

Late-Stage Pipeline

7%

12 trials in Phase 3/4

Results Transparency

67%

59 of 88 completed trials have results

Key Signals

17 recruiting59 with results38 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 1
79(48.2%)
Phase 2
69(42.1%)
Phase 3
12(7.3%)
N/A
4(2.4%)
164Total
Phase 1(79)
Phase 2(69)
Phase 3(12)
N/A(4)

Activity Timeline

Global Presence

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Clinical Trials (171)

Showing 20 of 171 trials
NCT05756569Phase 2Recruiting

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Role: collaborator

NCT03264131Phase 2Completed

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Role: collaborator

NCT06809140Phase 2Recruiting

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

Role: collaborator

NCT02091999Phase 1Completed

A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4

Role: collaborator

NCT05673928Phase 2Recruiting

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

Role: collaborator

NCT05775471Phase 2Recruiting

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

Role: collaborator

NCT01352520Phase 2Active Not Recruiting

SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)

Role: collaborator

NCT04700124Phase 3Active Not Recruiting

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-Eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Role: collaborator

NCT06011954Recruiting

A Study to Survey Adults in South Korea With Cancer Who Receive PADCEV Injection

Role: collaborator

NCT04685616Phase 3Recruiting

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Role: collaborator

NCT03924895Phase 3Active Not Recruiting

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

Role: collaborator

NCT04587687Phase 2Recruiting

Brentuximab Vedotin and Bendamustine for the Treatment of Relapsed or Refractory Follicular Lymphoma

Role: collaborator

NCT03755804Phase 2Active Not Recruiting

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Role: collaborator

NCT04225117Phase 2Active Not Recruiting

A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Role: collaborator

NCT05414500Phase 1Suspended

Mogamulizumab and Brentuximab Vedotin in CTCL and Mycosis Fungoides

Role: collaborator

NCT04457596Phase 3Active Not Recruiting

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Role: collaborator

NCT05239624Phase 2Recruiting

Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer

Role: collaborator

NCT01868451Not ApplicableCompleted

Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma

Role: collaborator

NCT04223856Phase 3Active Not Recruiting

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

Role: collaborator

NCT03275311Recruiting

Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008

Role: collaborator