Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

14.2%

236 terminated/withdrawn out of 1661 trials

Success Rate

83.7%

-2.8% vs industry average

Late-Stage Pipeline

41%

687 trials in Phase 3/4

Results Transparency

39%

467 of 1209 completed trials have results

Key Signals

53 recruiting467 with results180 terminated56 withdrawn

Enrollment Performance

Analytics

Phase 2
454(29.8%)
Phase 3
383(25.1%)
Phase 1
315(20.7%)
Phase 4
304(19.9%)
N/A
59(3.9%)
Early Phase 1
9(0.6%)
1524Total
Phase 2(454)
Phase 3(383)
Phase 1(315)
Phase 4(304)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (1661)

Showing 20 of 1661 trials
NCT01595984Phase 3Completed

Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)

Role: collaborator

NCT06167642Enrolling By Invitation

Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumab

Role: collaborator

NCT06629584Phase 2Recruiting

Phase II Study of Asciminib for Second-line Treatment of Chronic Phase Chronic Myeloid Leukemia

Role: collaborator

NCT06430671Phase 1Completed

Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis

Role: collaborator

NCT07443137Phase 1Not Yet Recruiting

CAR-T ceLL for Eradication of Active Residual Disease in LBCL (CLEAR-1 Study)

Role: collaborator

NCT03899155Phase 2Recruiting

Pan Tumor Rollover Study

Role: collaborator

NCT07145177Phase 1Recruiting

177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

Role: collaborator

NCT07618390Phase 2Not Yet Recruiting

A Phase ll, Interventional, Single-arm Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib and Fulvestrant in Chinese Patients With PIK3CA-mutant, HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer.

Role: collaborator

NCT07549139Not ApplicableNot Yet Recruiting

Overcoming Racial Disparities in Screening Mammography

Role: collaborator

NCT05843253Phase 2Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Role: collaborator

NCT05413915Phase 3Terminated

Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML

Role: collaborator

NCT02645149Phase 2Completed

Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma

Role: collaborator

NCT02693535Phase 2Recruiting

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Role: collaborator

NCT00159484Phase 1Completed

Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer

Role: collaborator

NCT06953882Phase 2Recruiting

Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy

Role: collaborator

NCT07237256Phase 3Recruiting

Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib

Role: collaborator

NCT05198479Phase 2Suspended

Phase II 177Lu-DOTATATE Study in Metastatic NPC With a Safety Run-in

Role: collaborator

NCT04239157Phase 2Recruiting

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Role: collaborator

NCT05944562Phase 1Active Not Recruiting

Tulmimetostat (DZR123) in Patients With Mycosis Fungoides and Sézary Syndrome

Role: collaborator

NCT05296746Phase 2Active Not Recruiting

Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer

Role: collaborator