Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task
Sodium Bicarbonate Supplementation Promotes Changes in Performance, Muscle Activity and Strength of Individuals Trained During the Performance of Intermittent and Intense Task? Randomized, Double-blind, Crossover Trial
1 other identifier
interventional
12
1 country
1
Brief Summary
The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 6, 2019
CompletedFirst Posted
Study publicly available on registry
February 12, 2019
CompletedStudy Start
First participant enrolled
October 20, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
November 30, 2019
CompletedOctober 17, 2019
October 1, 2019
10 days
February 6, 2019
October 16, 2019
Conditions
Outcome Measures
Primary Outcomes (2)
Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment
The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.
60 minutes
Peak torque assessed with isokinetic dynamometer equipment
The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.
60 minutes
Secondary Outcomes (1)
Lactate assessed with portable lactometer
15 seconds
Study Arms (2)
Alkalosis group
EXPERIMENTALThe subjects should receive gelatinous capsules containing 0.3 g.kg -1 of sodium bicarbonate
Placebo group
PLACEBO COMPARATORThe subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate
Interventions
The subjects should ingest 0.3g.kg of sodium bicarbonate 90 minutes before the beginning of the protocol task.
The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate
Eligibility Criteria
You may qualify if:
- resistance trained men (minimum 12 moths resistance training experience)
You may not qualify if:
- diabetes mellitus;
- respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders;
- acid-base balance disorder;
- continuous use of some type of medication;
- use of high-protein supplementation and creatine supplementation;
- users of anabolic steroids.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Nove de Julholead
- Marcelo Martins Kalytczakcollaborator
Study Sites (1)
Nove de Julho University
São Paulo, 06454050, Brazil
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
February 6, 2019
First Posted
February 12, 2019
Study Start
October 20, 2019
Primary Completion
October 30, 2019
Study Completion
November 30, 2019
Last Updated
October 17, 2019
Record last verified: 2019-10