Success Metrics

Clinical Success Rate
81.2%

Based on 56 completed trials

Completion Rate
81%(56/69)
Active Trials
14(14%)
Results Posted
32%(18 trials)
Terminated
13(13%)

Phase Distribution

Ph phase_1
12
12%
Ph early_phase_1
4
4%
Ph phase_3
12
12%
Ph phase_2
17
17%
Ph phase_4
19
19%
Ph not_applicable
36
35%

Phase Distribution

16

Early Stage

17

Mid Stage

31

Late Stage

Phase Distribution100 total trials
Early Phase 1First-in-human
4(4.0%)
Phase 1Safety & dosage
12(12.0%)
Phase 2Efficacy & side effects
17(17.0%)
Phase 3Large-scale testing
12(12.0%)
Phase 4Post-market surveillance
19(19.0%)
N/ANon-phased studies
36(36.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.2%

56 of 69 finished

Non-Completion Rate

18.8%

13 ended early

Currently Active

14

trials recruiting

Total Trials

102

all time

Status Distribution
Active(18)
Completed(56)
Terminated(13)
Other(15)

Detailed Status

Completed56
unknown15
Terminated13
Recruiting8
Active, not recruiting6
Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials
102
Active
14
Success Rate
81.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (4.0%)
Phase 112 (12.0%)
Phase 217 (17.0%)
Phase 312 (12.0%)
Phase 419 (19.0%)
N/A36 (36.0%)

Trials by Status

unknown1515%
not_yet_recruiting44%
completed5655%
recruiting88%
active_not_recruiting66%
terminated1313%

Recent Activity

Clinical Trials (102)

Showing 20 of 102 trialsScroll for more
NCT04984226Phase 2

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

Recruiting
NCT07424625Phase 4

A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients

Not Yet Recruiting
NCT05113641Not Applicable

Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)

Active Not Recruiting
NCT05697770Phase 3

SODium BICarbonate for Metabolic Acidosis in the ICU

Active Not Recruiting
NCT05853692Not Applicable

Prevention of Oral Mucositis in Head and Neck Cancer.

Recruiting
NCT05564130Phase 4

Bicarbonate for In-Hospital Cardiac Arrest

Active Not Recruiting
NCT04651088Early Phase 1

Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet

Not Yet Recruiting
NCT07408076Phase 1

Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones

Not Yet Recruiting
NCT07321379Not Applicable

Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour

Not Yet Recruiting
NCT05928936Phase 2

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

Recruiting
NCT05328180Not Applicable

aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)

Active Not Recruiting
NCT06999993Phase 2

Efficacy and Safety of Sodium Hyaluronate Gel Combined With Sodium Bicarbonate Versus Sodium Bicarbonate Alone in Prevention of Failed Back Surgery Syndrome

Active Not Recruiting
NCT06335537Phase 1

Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers

Recruiting
NCT00639912Phase 4

Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.

Completed
NCT05005793Phase 4

Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

Recruiting
NCT06047366Phase 4

Combination of Buffered Anesthetic to Treat Mandibular Molars

Terminated
NCT02411773Phase 1

Sympatholysis in Chronic Kidney Disease

Recruiting
NCT03461354Not Applicable

MucoLox Formulation to Mitigate Mucositis Symptoms in Head/Neck Cancer

Terminated
NCT06622525Not Applicable

Use of Sodium Bicarbonate As Prophylaxis for Kidney Damage in Patients with Heatstroke

Recruiting
NCT06186622Phase 1

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Completed

Drug Details

Intervention Type
DRUG
Total Trials
102