NCT03778424

Brief Summary

This is an extended access study for participants who have completed Rufinamide Study E2080-G000-303 to continue to have access to rufinamide until it becomes commercially available in Poland or until no participants remain in the EAP.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 27, 2018

Completed
22 days until next milestone

First Posted

Study publicly available on registry

December 19, 2018

Completed
Last Updated

July 17, 2025

Status Verified

July 1, 2025

First QC Date

November 27, 2018

Last Update Submit

July 14, 2025

Conditions

Keywords

Central Nervous SystemE2080RufinamideEpilepsySeizuresBrain Diseases

Interventions

Rufinamide up to 45 milligram per kilogram per day (mg/kg/day).

Eligibility Criteria

Age4 Years+
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Participants who were on rufinamide treatment and have completed Study E2080-G000-303 in Poland.

You may not qualify if:

  • Participants were randomized to the other antiepileptic drug (AED) treatment group in study E2080-G000-303.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Generała Tadeusza Kościuszki 52

Kielce, Poland

AVAILABLE

Szpital Kliniczny im. Heliodora Święcickiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu

Poznan, Poland

AVAILABLE

MeSH Terms

Conditions

Lennox Gastaut SyndromeEpilepsySeizuresBrain Diseases

Interventions

rufinamide

Condition Hierarchy (Ancestors)

Epileptic SyndromesCentral Nervous System DiseasesNervous System DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Eisai Medical Information

CONTACT

Study Design

Study Type
expanded access
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 27, 2018

First Posted

December 19, 2018

Last Updated

July 17, 2025

Record last verified: 2025-07

Locations