Lennox Gastaut Syndrome
22
5
8
7
Key Insights
Highlights
Success Rate
88% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 17/100
4.5%
1 terminated out of 22 trials
87.5%
+1.0% vs benchmark
32%
7 trials in Phase 3/4
43%
3 of 7 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 7 completed trials
Clinical Trials (22)
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
Pallidothalamic Tracts Electrical Stimulation for Lennox-Gastaut Syndrome
Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY
RNS System LGS Feasibility Study
A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome
An Extended Access Program (EAP) for Perampanel
BMB-101 in Absence Epilepsy and DEE
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303
A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome
Intermediate-Size Expanded Access Protocol (EAP) for LP352
Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies
Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
Carisbamate Safety Study in Adult and Pediatric Subjects With Lennox-Gastaut Syndrome
A Study to Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol
Add-on Therapy With Low Dose Fenfluramine in Lennox Gastaut Epilepsy
Carisbamate in Adult & Pediatric Subjects With Lennox-Gastaut Syndrome
Long-term Cardiac Monitoring in Epilepsy
Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults