Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

14.4%

76 terminated/withdrawn out of 526 trials

Success Rate

83.9%

-2.6% vs industry average

Late-Stage Pipeline

26%

137 trials in Phase 3/4

Results Transparency

65%

257 of 397 completed trials have results

Key Signals

13 recruiting257 with results60 terminated16 withdrawn

Enrollment Performance

Analytics

Phase 2
176(35.5%)
Phase 1
173(34.9%)
Phase 3
97(19.6%)
Phase 4
40(8.1%)
N/A
7(1.4%)
Early Phase 1
3(0.6%)
496Total
Phase 2(176)
Phase 1(173)
Phase 3(97)
Phase 4(40)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (526)

Showing 20 of 526 trials
NCT06384573Phase 3Active Not Recruiting

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Role: collaborator

NCT05269394Phase 2Active Not Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Role: collaborator

NCT01760005Phase 2Active Not Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Role: collaborator

NCT07723950Not Yet Recruiting

A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease

Role: lead

NCT04949256Phase 3Completed

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

Role: collaborator

NCT06274528Phase 2Recruiting

DORA and LP in Alzheimer's Disease Biomarkers

Role: collaborator

NCT04015141Phase 2Active Not Recruiting

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

Role: lead

NCT03778424Unknown

An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303

Role: lead

NCT02623972Phase 2Active Not Recruiting

A Phase 2 Study of Eribulin Followed by AC as Preoperative Therapy for HER2-negative Inflammatory Breast Cancer

Role: collaborator

NCT04645602Phase 2Recruiting

Merck IIT: RRP Pembro and Lenvatinib

Role: collaborator

NCT04321954Phase 2Completed

Lenvatinib in Locally Advanced Invasive Thyroid Cancer

Role: collaborator

NCT04986579Phase 2Recruiting

Scalp Cooling in MBC

Role: collaborator

NCT05024994Phase 2Completed

A Study of E7820 in People With Bone Marrow (Myeloid) Cancers

Role: collaborator

NCT03264664Phase 1Active Not Recruiting

Study of E7386 in Participants With Selected Advanced Neoplasms

Role: lead

NCT04300556Phase 1Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

Role: lead

NCT04468659Phase 3Active Not Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Role: lead

NCT02780310Phase 2Active Not Recruiting

Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma

Role: collaborator

NCT03275311Recruiting

Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008

Role: collaborator

NCT06188559Phase 2Completed

A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer

Role: lead

NCT04246177Phase 3Completed

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Role: collaborator