Compression Garments for Recovery in Modern Pentathletes

NCT03707067 | Unknown

• 1 other identifier: SMU_SHAS_2018_02
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 2

Brief Summary

Aims To assess the efficacy of made to measure, high pressure compression garments (CG) for facilitating the recovery of strength, muscular power, and physiological markers of muscle damage following fencing, when compared a sham treatment Rationale for study design The results of a recent meta-analysis have informed the design of this study. The conclusions of the meta-analysis were that CG are most effective for the recovery of:

• Force and power performance following eccentric/plyometric exercise
• Maximal force production, at least 24 hours post-exercise (for example in strength and power athletes undertaking resistance training programmes)
• Additionally, the recovery of high-intensity cardiovascular performance may also be enhanced by the used of CG, when tested 24 hours following exercise which incurs metabolic stress Accordingly, the current study was designed to investigate the effects of CG of intense, competitive sparring following fencing sessions, held at the British Modern Pentathlon training base at the University of Bath.

Conditions

Muscle Damage

Keywords

exercise induced muscle damage; elite athlete; recovery

Outcome Measures

Primary Outcomes (3)

• Maximal isometric voluntary contraction strength for knee extension (change in Newtons compared to baseline)

  Participants will be assessed for strength performance with maximal isometric voluntary contraction of the knee extensors (using a strain gauge) at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover).

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• Lower body reactive strength (jump height/contact time in m/s) following a drop from a 0.6 m box onto a force plate (change in m/s compared to baseline)

  Participants will be compared to baseline for reactive strength performance at the following time-points after fencing:Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). Jump height (m) and contact time (s) will be recorded following a drop from a 0.6 m box onto a force-plate.

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• 3200 m run time trial performance (change in seconds compared to baseline)

  Participants will be timed for 3200 m running performance at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover).

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

Secondary Outcomes (5)

• Perceived soreness, scored by drawing a vertical line on a 200 mm visual analogue scale from 0 mm (no soreness) to 200 mm (worst soreness imaginable). Change in mm will be compared to baseline.

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• Circulating creatine kinase concentrations (CK - change in international units compared to baseline)

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• Mid-thigh girth (MTG) at the mid-thigh skinfold site as defined by International Society of Anthropometry and Kinanthropometry. Change will be measured in mm by comparing to baseline

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• Free oxygen radicals defense (FORD) status (change in mmol/L Trolox equivalents compared to baseline)

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

• Free oxygen radicals (FORT) status (change in mmol/L H2O2 equivalents compared to baseline)

  36 h. Second leg will be conducted after 1 week "washout" (10 days in total)

Study Arms (2)

Custom fitted compression garments

EXPERIMENTAL

Made-to-measure compression garments providing high pressures (\> 30 mmHg at the ankle and \>20 mmHg at the thigh - equivalent to European class-2 stockings)

Device: Compression garments

Sham recovery drink

SHAM COMPARATOR

Non-caloric beverage, labelled as a "recovery" drink to enhance athletic recovery. Aspartame/acesulfame-k based sweetener, providing 0.5 g carbohydrate and 2 Kcal per serving

Other: Sham recovery drink

Interventions

Compression garments DEVICE

Made-to-measure compression garments providing high pressures (\> 30 mmHg at the ankle and \>20 mmHg at the thigh - equivalent to European class-2 stockings)

Custom fitted compression garments

Sham recovery drink OTHER

Non-caloric beverage, labelled as a "recovery" drink proposed to enhance athletic recovery. Aspartame/acesulfame-k based sweetener, providing 0.5 g carbohydrate and 2 Kcal per serving

Sham recovery drink

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Athletes must be full-time athletes over the age of 18
• Training regularly for at least 3 months without extended disruption to training (\> 2 weeks)

You may not qualify if:

• Presentation of injuries or chronic illnesses
• Inactivity or disruptions to training \> 2 weeks (e.g. due to injury)
• The use of anti-inflammatory medications
• Over 40 years old (classification as a "Masters" athlete)

Sponsors & Collaborators

• St Mary's University College: lead
• Modern Pentathlon GB: collaborator

Study Sites (2)

University of Bath

Bath, Somerset, BA2 7AY, United Kingdom

COMPLETED

St Marys University

London, TW1 4SX, United Kingdom

RECRUITING

Related Publications (2)

• Brown F, Gissane C, Howatson G, van Someren K, Pedlar C, Hill J. Compression Garments and Recovery from Exercise: A Meta-Analysis. Sports Med. 2017 Nov;47(11):2245-2267. doi: 10.1007/s40279-017-0728-9.

  PMID: 28434152 BACKGROUND

• Brophy-Williams N, Driller M, Halson S, Fell J, Shing C. Evaluating the Kikuhime pressure monitor for use with sports compression clothing. Sports Engineering. 2014;17(1):55-60

  BACKGROUND

Central Study Contacts

Freddy Brown, PhD

CONTACT

07746075161; freddybrown1984@gmail.com

Jessica Hill, PhD

CONTACT

020 8240 4283; jessica.hill@stmarys.ac.uk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Randomization carried out and compression garments allocated by a third party. All testing will be completed once athletes have removed their garments, without the knowledge of outcomes assessors or primary investigator
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Crossover RCT

Study Record Dates

• First Submitted: June 7, 2018
• First Posted: October 16, 2018
• Study Start: November 30, 2018
• Primary Completion: December 31, 2018
• Study Completion: February 28, 2019
• Last Updated: November 5, 2018

Record last verified: 2018-10

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR
• Time Frame: Study Protocol, Statistical Analysis Plan (SAP), Informed Consent Form (ICF) and Clinical Study Report (CSR) will all be available from February 2019. Data will be stored for 10 years
• Access Criteria: Must demonstrate planned research protocol and ethics application

Locations

GB (2)