Effects of Aerobic and Resistance Training on Abdominal Fat Loss

NCT03700827 | Terminated DMC

• 1 other identifier: 16-1208-4C-2
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

Study the effects of different exercise modes on total and regional adiposity variation in subcutaneous and visceral adipose tissue (VAT and SAT). The investigators hypothesize that total abdominal will improve for all the exercise groups compared to the control group. When comparing intervention groups: 1) no differences on the degree of improvement in total abdominal fat depots (VAT and SAT) 2) different degree of change when comparing specific sections at VAT and SAT are expected.

Conditions

Obesity, Abdominal

Keywords

Abdominal Fat; Visceral Adipose Tissue; Subcutaneous Adipose Tissue; Exercise; Intervention

Outcome Measures

Primary Outcomes (1)

• Changes in Visceral Abdominal Tissue (VAT)

  Changes in VAT will be measured using Magnetic Resonance Imaging

  2 assessment periods: at baseline and week 4

Secondary Outcomes (13)

• Changes in Subcutaneous Abdominal Tissue (SAT)

  2 assessment periods: at baseline and week 4

• Changes in Muscular Strength

  2 assessment periods: at baseline and week 4

• Changes in Cardiorespiratory Function

  2 assessment periods: at baseline and week 4

• Changes in fat mass (kg)

  2 assessment periods: at baseline and week 4

• Changes in relative body fat (%BF)

  2 assessment periods: at baseline and week 4

Study Arms (3)

Resistance Training Group

EXPERIMENTAL

Resistance training will consist of 3 whole body circuits per week for 3 weeks lasting approximately 1 hour per session. All major muscle groups will be involved (leg press, bent-over-row, bench press, back squat, dumbbell jump squats, dead-lifts, and weighted abdominal crunches). Each participant will go through each circuit three times with 30 seconds between each exercise and 2 minutes between each set.

Other: Resistance Training

Aerobic Training Group

EXPERIMENTAL

Aerobic interval training will consist of 3 sessions/week for 3 weeks for approximately 45-50 minutes per session depending on exercise energy expenditure. There will be two periods of intervals. The first period will be 3 minutes of high-intensity activity and the second period will be reduced to moderate-intensity for 2 minutes. The speed/incline will change depending on the participants perception or Borg's rating of perceived exertion. Intensity will be measured using Lactate levels after each session.

Other: Aerobic Training

Control Group

NO INTERVENTION

The control group must attend sessions but will not exercise.

Interventions

Resistance Training OTHER

High-intensity Resistance Training Group

Resistance Training Group

Aerobic Training OTHER

Aerobic Interval Training Group

Aerobic Training Group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• kg/m2 BMI
• White/Caucasian
• Female
• Sedentary

You may not qualify if:

• Known cardiovascular, pulmonary, metabolic disease
• Pregnant females
• Any excluded criteria with MRI scans (i.e. certain metal implants, recent tattoos)
• Diabetic
• Hypertension
• Cigarette smoking
• MRI related contraindications (metal, no removable devices, etc.)

Sponsors & Collaborators

• Southern Illinois University Edwardsville: lead
• Washington University School of Medicine: collaborator

Study Sites (1)

Southern Illinois University of Edwardsville

Edwardsville, Illinois, 62026, United States

Location

MeSH Terms

Conditions

Obesity, Abdominal; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Obesity; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Maria Fernandez del Valle, PhD

  Southern Illinois University of Edwardsville

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2018
• First Posted: October 9, 2018
• Study Start: October 1, 2017
• Primary Completion: April 1, 2020
• Study Completion: May 1, 2020
• Last Updated: October 4, 2021

Record last verified: 2021-03

Locations

US (1)