Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

18.6%

400 terminated/withdrawn out of 2151 trials

Success Rate

75.2%

-11.3% vs industry average

Late-Stage Pipeline

154 trials in Phase 3/4

Results Transparency

54%

659 of 1214 completed trials have results

Key Signals

267 recruiting659 with results280 terminated120 withdrawn

Enrollment Performance

Analytics

N/A

877(49.6%)

Phase 2

337(19.1%)

Phase 1

328(18.6%)

Phase 4

84(4.8%)

Early Phase 1

72(4.1%)

Phase 3

70(4.0%)

1768Total

N/A(877)

Phase 2(337)

Phase 1(328)

Phase 4(84)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (2151)

Showing 20 of 2151 trials

NCT07072481Not ApplicableRecruiting

Sustaining Innovative Tools to Expand Youth-Friendly HIV Self-Testing

Role: lead

NCT00593840Phase 2Active Not Recruiting

Phase II Trial Evaluating Elimination of Radiation Therapy

Role: lead

NCT05918029Phase 2Terminated

Bone in CKD Alkali Response (BICARb Pilot Trial)

Role: collaborator

NCT07731256Phase 2Not Yet Recruiting

Semaglutide for Low Back Pain

Role: lead

NCT06518577Phase 4Completed

Immunogenicity of Influenza Vaccinations

Role: collaborator

NCT05552157Phase 2Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Role: lead

NCT05269394Phase 2Active Not Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Role: lead

NCT06529809Phase 1Recruiting

Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer

Role: lead

NCT06647498Phase 2Recruiting

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Role: lead

NCT06384573Phase 3Active Not Recruiting

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Role: lead

NCT01760005Phase 2Active Not Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Role: lead

NCT05616624Phase 1Terminated

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Role: lead

NCT07453459Not ApplicableRecruiting

Feasibility of HPV Self-Collection Kits for Cervical Cancer Screening

Role: lead

NCT02476786Phase 2Recruiting

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Role: lead

NCT05671224Not ApplicableCompleted

Visual Aids for Induction of Labor RCT