NCT03652207

Brief Summary

The study aims to assess body weight and body composition changes in overweight and obese persons consuming an energy-reduced diet containing foods with either sucrose or isomaltulose (Palatinose(TM)) over a period of 3 months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 20, 2009

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2010

Completed
8.2 years until next milestone

First Submitted

Initial submission to the registry

August 27, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 29, 2018

Completed
Last Updated

August 29, 2018

Status Verified

August 1, 2018

Enrollment Period

1.2 years

First QC Date

August 27, 2018

Last Update Submit

August 27, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Body Weight Change

    Body weight Change over a 12-week period

    12 weeks

Secondary Outcomes (4)

  • Body fat percentage

    12 weeks

  • postprandial respiratory quotient (RQ)

    120 minutes postprandial

  • BMI

    12 weeks

  • Waist circumference

    12 weeks

Study Arms (2)

Sucrose

PLACEBO COMPARATOR

Test products i.e. low-fat yogurt drink, fruits drink and sweetener sachet for cereals containing sucrose

Other: Sucrose

Palatinose(TM)

EXPERIMENTAL

Test products i.e. low-fat yogurt drink, fruits drink and sweetener sachet for cereals containing isomaltulose (Palatinose™)

Other: isomaltulose (Palatinose(TM)

Interventions

isomaltulose containing food products, i.e. low-fat yogurt drink, fruits drink and sweetener sachet for cereals, consumed within an energy-reduced diet

Palatinose(TM)
SucroseOTHER

sucrose containing food products, i.e. low-fat yogurt drink, fruits drink and sweetener sachet for cereals, consumed within an energy-reduced diet

Sucrose

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Subject is healthy at the time of pre-examination
  • Subject has a BMI of 25 - 35 kg/m² and motivated to lose weight
  • Subject is aged 18 - 60 years at the time of pre-examination

You may not qualify if:

  • Person suffers from an acute or chronic disease
  • Person has known dietary restrictions or allergies to Foods
  • Intake of medications which interfere with body composition, appetite, satiety or food intake

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oxford Brookes University

Oxford, OX3 0BP, United Kingdom

Location

Related Publications (1)

  • Maresch CC, Petry SF, Theis S, Bosy-Westphal A, Linn T. Low Glycemic Index Prototype Isomaltulose-Update of Clinical Trials. Nutrients. 2017 Apr 13;9(4):381. doi: 10.3390/nu9040381.

    PMID: 28406437BACKGROUND

MeSH Terms

Conditions

OverweightObesityBody Weight

Interventions

isomaltuloseSucrose

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

DisaccharidesOligosaccharidesPolysaccharidesCarbohydratesSugars

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 27, 2018

First Posted

August 29, 2018

Study Start

April 20, 2009

Primary Completion

June 30, 2010

Study Completion

June 30, 2010

Last Updated

August 29, 2018

Record last verified: 2018-08

Data Sharing

IPD Sharing
Will not share

Locations