Effects of Sucrose Added Blind to the Diet Over Eight Weeks on Body Mass and Weight in Men

NCT04804397 | Completed

• 1 other identifier: PSY4272
• Study Type: interventional
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Background: Sugar intake, especially in liquid, correlates with obesity. Yet, whether it is a special cause of obesity is less clear. Few experimental studies exist. Aim: To replicate the investigators' previous 4 week experiments on women with men over 8 weeks to ascertain if: they gain weight given sucrose soft drinks; mood is affected; energy intake is affected. Participants: 80 men BMI 25-35, aged 30-55. Procedure: After a week of baseline, over eight weeks single blind 40 men received soft drinks containing sucrose (1650 KJ, 97g carbohydrate per day), 40 received control drinks. A three-day food diary with mood ratings and activity levels was completed during baseline and weeks 1, 4 and 8 of the experiment. Body mass was recorded weekly with other anthropometric measures.

Conditions

Overweight

Keywords

Sucrose; Sugar; Carbohydrate; Weight gain; men

Outcome Measures

Primary Outcomes (1)

• Body Mass

  Do participants gain weight?

  Eight Weeks

Secondary Outcomes (2)

• Daily energy intake assessed by free-living unweighed food diary

  Eight Weeks

• Mood assessed using 10 rating scales

  Eight Weeks

Study Arms (2)

Sucrose

EXPERIMENTAL

Sucrose: 1l sucrose sweetened soft drink per day for 8 weeks (1650 KJ, 97g carbohydrate per day) as 4 25cl drinks

Dietary Supplement: Sucrose

Aspartame

PLACEBO COMPARATOR

Aspartame: 1l aspartame sweetened soft drink per day for 8 weeks as 4 25cl drinks

Dietary Supplement: Sucrose

Interventions

Sucrose DIETARY_SUPPLEMENT

Sucrose sweetened soft drinks

Also known as: Aspartame, Aspartame sweetened soft drinks as comparator

Aspartame; Sucrose

Eligibility Criteria

• Age: 30 Years - 55 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• BMI 25-35

You may not qualify if:

• Diabetes,
• other health problems,
• medication,
• dislike of soft drinks

Sponsors & Collaborators

• University of Hull: lead

MeSH Terms

Conditions

Overweight; Weight Gain; Multiple Endocrine Neoplasia Type 1

Interventions

Sucrose; Aspartame

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Body Weight Changes; Multiple Endocrine Neoplasia; Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Neoplasms, Multiple Primary; Neoplastic Syndromes, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Disaccharides; Oligosaccharides; Polysaccharides; Carbohydrates; Sugars; Dipeptides; Oligopeptides; Peptides; Amino Acids, Peptides, and Proteins

Study Officials

• Richard Hammersley, PhD

  University of Hull

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Health Psychology

Study Record Dates

• First Submitted: January 26, 2016
• First Posted: March 18, 2021
• Study Start: August 1, 2010
• Primary Completion: June 1, 2013
• Study Completion: June 1, 2013
• Last Updated: March 18, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share