NCT03422185

Brief Summary

Cross-sectional survey of all adults residing in two defined geographical regions in urban Lilongwe and rural Karonga District. Participants were interviewed, had anthropometric measures taken, and had fasting blood specimens taken.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28,891

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2013

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2013

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2015

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

January 30, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 5, 2018

Completed
Last Updated

April 17, 2018

Status Verified

April 1, 2018

Enrollment Period

1.8 years

First QC Date

January 30, 2018

Last Update Submit

April 13, 2018

Conditions

HypertensionDiabetesOverweight and Obesity

Outcome Measures

Primary Outcomes (1)

  • What is the true burden of hypertension, diabetes, and hyperlipidaemia?

    Prevalence of hypertension (BP \<140/90 or self-report of antihypertensive use), diabetes (fasting blood glucose \>7.0 or self-report history of diabetes), and hyperlipidaemia

    By end of 2018

Secondary Outcomes (2)

  • What is the prevalence of known risk factors - notably smoking, obesity, physical inactivity, alcohol, salt, and saturated fat intake?

    By end of 2020

  • Is infection, notably HIV infection or its therapy, associated with increased risk of NCDs?

    By end of 2020

Interventions

No interventionOTHER

No intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All adults within 2 defined geographical areas - one in urban Lilongwe, one in rural Karonga District

You may qualify if:

  • all adults over 18 self-identifying as normally resident in the pre-defined geographical areas

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MEIRU

Lilongwe, Malawi

Location

Related Publications (1)

  • Prynn JE, Banda L, Amberbir A, Price AJ, Kayuni N, Jaffar S, Crampin AC, Smeeth L, Nyirenda M. Dietary sodium intake in urban and rural Malawi, and directions for future interventions. Am J Clin Nutr. 2018 Sep 1;108(3):587-593. doi: 10.1093/ajcn/nqy125.

    PMID: 29982267DERIVED

MeSH Terms

Conditions

HypertensionDiabetes MellitusOverweightObesity

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesOvernutritionNutrition DisordersBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 30, 2018

First Posted

February 5, 2018

Study Start

May 1, 2013

Primary Completion

February 1, 2015

Study Completion

February 1, 2015

Last Updated

April 17, 2018

Record last verified: 2018-04

Locations

MA(1)