Thyroid Function and Diabetes Complications

NCT03001336 | Completed

• 1 other identifier: DIA-THY-1
• Study Type: observational
• Target: 260
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to investigate the potential association between thyroid function and diabetes complications in the elderly subjects with type 2 diabetes mellitus (T2DM).

Conditions

Diabetes; Thyroid Disease

Keywords

Thyroid; Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

• Diabetic retinopathy which is diagnosed by the measurement of fundus fluorescein angiography. (Diabetic retinopathy is clinically graded based on the international clinical diabetic retinopathy severity scales.)

  Day One

Secondary Outcomes (1)

• 24h-albuminuria

  Day One

Interventions

no intervention OTHER

This is a cross-sectional study

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with type 2 diabetes who visited in the Department of Endocrinology at the Nanjing First Hospital from January 2011 to December 2012 were enrolled in this study.

You may qualify if:

• Patients are ≥ 60 years old, with T2DM and the diagnostic criteria of T2DM is according to the World Health Organization in 1999.
• Patients have normal thyroid function and negative for thyroid autoantibodies, such as thyroid peroxidase antibody (TPOAb) or thyroglobulin antibody (TGAb).

You may not qualify if:

• Patients with a history of thyroid disease or chronic liver disease or nondiabetic renal problems or cancer.
• Patients use systemic drug therapy such as thyroxine, anti-thyroid drugs, glucocorticoids and oral contraceptives.
• Patients are pregnant or lactating women.
• Patients with acute intercurrent illness of diabetes.
• Patients with an acute infection.
• Patients with a history of drug abuse alcohol dependence in the past 5 years.

Sponsors & Collaborators

• Nanjing First Hospital, Nanjing Medical University: lead

MeSH Terms

Conditions

Diabetes Mellitus; Thyroid Diseases

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 12, 2016
• First Posted: December 23, 2016
• Study Start: December 1, 2010
• Primary Completion: December 1, 2012
• Study Completion: May 1, 2013
• Last Updated: December 23, 2016

Record last verified: 2011-01

Data Sharing

• IPD Sharing: Will not share