Response Inhibition to High Calorie Food Cues Among Adolescents Following Active and Sedentary Video Game Play

NCT03407352 | Completed

• 1 other identifier: X15365
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

Response inhibition is a cognitive process that helps individuals suppress or avoid unwanted actions and inappropriate behavior. In regards to food, response inhibition allows a person to resist eating, ignore poor food choices and poor behavior related to food choices. Previous research suggests that physical activity may play a role in the regulation of response inhibition to food in adults. The purpose of this study is to compare the effects of an acute bout of active video gaming versus passive video gaming on response inhibition to high calorie and low calorie food images among adolescents. The proposed study is a randomized cross-over study with counterbalanced design. Participants will come to the lab two times. Each subject will serve as their own control. There will be two conditions and all participants will complete both conditions. One condition will be completed each time the participants come to the lab. The two conditions will include (a) 60 minutes of sedentary video game play and (b) 60 minutes of active video game play at moderate-intense levels. After each video game condition the participants will view pictures of high-calorie and low-calorie foods while being connected to an EEG machine. The EEG will measure the N2 and P3 event-related potentials, which will be used to index and analyze response inhibition. As participants view the pictures of high-calorie and low-calorie foods, they will be given a button pressing task where the press a button when they see pictures of the high-calorie or low-calorie foods. Immediately after each video game session participants will complete two cognitive measurement tasks. These tasks are (a) Stroop color-word task and (b) auditory verbal learning test. The Stroop color-word test requires the participants to read words typed in different colors on a sheet of paper and to say the name of the color of ink the words are printed in (ie to say "blue" when the word "red" is printed in blue ink). The auditory verbal learning test will require the researchers to read a list of 15 words and have participants repeat as many of the words back to the researcher as possible. This will be repeated 6 times. After the 5th time, there will be a 30 minute waiting period before the 6th trial where participants will be allowed to eat ad libitum pre-weighed foods while they wait to complete the last trial of the verbal learning test.

Conditions

Obesity

Keywords

Exercise; Video Games; Physical Activity; Children; Appetite

Outcome Measures

Primary Outcomes (1)

• Response inhibition

  Electrical activity of the brain will be recorded using EEG techniques using the Electrical Geodesics amplifier system (EGI: Electrical Geodesics Inc, Eugene OR) during the Go/No Go tasks. The EEG will be recorded continuously with a sampling rate of 250 Hz using a 24-bit analog-to-digital converter. The vertex sensor will be used as the reference electrode. Impedances will be kept below 50 kΩ according to EGI guidelines. A right posterior electrode approximately two inches behind the right mastoid will serve as the common ground. Electroencephalographic data will be segmented off-line and single trial epochs rejected if voltages exceed 100 µV, transitional (sample-to-sample) thresholds were greater than 100 µV or eye-channel amplitudes were above 70 µV. Data will be digitally re-referenced to an average reference then digitally low-pass filtered at 30Hz.

  Immediately within 15 minutes post intervention

Secondary Outcomes (3)

• Memory

  Within 45 minutes post intervention

• Hunger

  Before and immediately after the intervention

• Executive Function

  Within 15 minutes post intervention

Other Outcomes (1)

• Energy Expenditure

  This will be measured twice for 60 minutes during each gaming condition

Study Arms (2)

Passive Video Game Play

ACTIVE COMPARATOR

Participants will play video games in a seated position for 60 minutes.

Behavioral: Passive Video Game Play

Active Video Game Play

EXPERIMENTAL

Participants will play dance dance revolution (video game that requires lower body movement) for 60 minutes.

Behavioral: Active Video Game Play

Interventions

Active Video Game Play BEHAVIORAL

60 minutes of active video game play at a moderate intensity

Active Video Game Play

Passive Video Game Play BEHAVIORAL

60 minutes of passive video game play

Passive Video Game Play

Eligibility Criteria

• Age: 12 Years - 15 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Participants must have normal or corrected to normal vision. Participants must be able to participate in moderate-intensity physical activity without restrictions as measured by a physical activity readiness questionnaire (PAR-Q).

You may not qualify if:

• Participants will be excluded if they do not provide proper assent and written consent from guardians, have chronic or metabolic disease, have orthopedic impairments, have been diagnosed with an eating disorder (ie anorexia, bulimia or binge eating disorder), take medications that alter metabolism, appetite or neurological function, have a diagnosed learning disability, neurological disorder, brain injury or attention deficit/hyperactive disorder or have food allergies.

Sponsors & Collaborators

• Brigham Young University: lead

Study Sites (1)

Health and Human Performance Research Center

Provo, Utah, 84602, United States

Location

Related Publications (35)

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MeSH Terms

Conditions

Obesity; Motor Activity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Bruce W Bailey, PhD

  Brigham Young University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 26, 2016
• First Posted: January 23, 2018
• Study Start: June 1, 2016
• Primary Completion: September 1, 2017
• Study Completion: October 1, 2017
• Last Updated: February 21, 2019

Record last verified: 2019-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)