Protein Supplementation and Mixed Power Training on Muscle Function and Functional Capacities in Elderly Men

NCT03393650 | Completed

• 1 other identifier: UQAM
• Study Type: interventional
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in elderly men.

Conditions

Dynapenia; Aging; Physical Impairment

Keywords

exercise; protein; muscle function; aging

Outcome Measures

Primary Outcomes (1)

• Change in walking speed

  evaluate using the 4m- normal walking speed (m/sec)

  Change from Baseline walking speed at 12 weeks measure in all subjects

Secondary Outcomes (1)

• Change in lower limb muscle quality

  Change from Baseline lower limb muscle quality at 12 weeks measure in all subjects

Other Outcomes (1)

• Change in mitochondrial activity

  Change from Baseline mitochondrial activity at 12 weeks measure in half of the subjects

Study Arms (2)

Exercise + Placebo group

ACTIVE COMPARATOR

50 subjects will receive a placebo supplementation with an exercise intervention (EX group)

Other: Exercise + Placebo group

Exercise + Protein group

ACTIVE COMPARATOR

50 subjects will receive a protein supplementation combined with an exercise intervention (PROTEX group)

Other: Exercise + Protein group

Interventions

Exercise + Placebo group OTHER

1/2 of the subject will follow a mixed power training: 4 power exercises + 6 functional exercises combined to a placebo

Exercise + Placebo group

Exercise + Protein group OTHER

1/2 of the subject will receive 30 g/ d of protein (leucine+ vitD; divided in three equal doses: morning, afternoon and evening) + will follow a mixed power training: 4 power exercises + 6 functional exercises.

Exercise + Protein group

Eligibility Criteria

• Age: 60 Years+
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Elderly men
• years and older
• Sedentary men
• Not obese (BMI \<30 kg/m2)
• Living in free-living community

You may not qualify if:

• Not able to follow an exercise program (doctor authorization: XAAP)
• Having Lactose intolerance
• Having Pace marker
• Having Metabolism disorder
• No weight stable since the last 6 months
• No stable medication (same dose and type since at least 6 months)

Sponsors & Collaborators

• Université du Québec a Montréal: lead

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• mylene aubertin-leheudre, PhD

  Université du Québec a Montréal

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: December 15, 2016
• First Posted: January 8, 2018
• Study Start: September 1, 2013
• Primary Completion: December 1, 2015
• Study Completion: December 1, 2015
• Last Updated: January 8, 2018

Record last verified: 2018-01