NCT03332693

Brief Summary

The aim of this study is to determine whether individuals differ one from the other in their genetic, cellular, systemic, structural and functional response to acute exercise.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2017

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

November 2, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 6, 2017

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2019

Completed
Last Updated

November 6, 2017

Status Verified

November 1, 2017

Enrollment Period

2 years

First QC Date

November 2, 2017

Last Update Submit

November 2, 2017

Conditions

Physical Exertion

Outcome Measures

Primary Outcomes (1)

  • Genetic polymorphism changes in knee muscles

    Genetic analysis will be made through a blood test and biopsy of knee muscle and results will be compared

    One year

Study Arms (3)

No exercise

ACTIVE COMPARATOR

Volunteers will not participate in exercise

Other: No exercise

Light exercise

ACTIVE COMPARATOR

Volunteers will participate in one short exercise

Other: Exercise

Heavy exercise

ACTIVE COMPARATOR

Volunteers will participate in heavy exercise

Other: Exercise

Interventions

ExerciseOTHER

Leg weight raising

Heavy exerciseLight exercise
No exerciseOTHER

Volunteers will not participate in exercise

No exercise

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy adults

You may not qualify if:

  • Unhealthy adults

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hillel Yaffe Medical Center

Hadera, 38100, Israel

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Eias Kassem, MD

    Hillel Yaffe Medical Center

    STUDY DIRECTOR

  • Sigal Ben Zaken, PhD

    Wingate Academic College for Physical Education and Sport Sciences

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Eias Kassem, MD

CONTACT

972-6246882eiask@hy.health.gov.il

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 2, 2017

First Posted

November 6, 2017

Study Start

November 1, 2017

Primary Completion

November 1, 2019

Study Completion

November 1, 2019

Last Updated

November 6, 2017

Record last verified: 2017-11

Locations

IL(1)