Resilience for Older Workers With OA Through Exercise

NCT02609672 | Completed Results DMC

• 1 other identifier: ResilienceAtWork
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Exercise is effective at reducing pain while improving physical function. However we do not know if exercise can boost resilience in the workplace, to allow people with osteoarthritis to work as long as they desire. Previous research shows that exercise holds the most promise for helping people enjoy their work because it reduces sick time, reduces pain, and improves productivity. However, little work has examined the effect of exercise for people with arthritis in the workplace. The purpose of the study is to investigate whether exercise improves resilience in the workplace, mobility, fitness, strength, and pain in comparison to no exercise in those with knee and/or hip osteoarthritis.

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip

Keywords

Exercise; Resilience

Outcome Measures

Primary Outcomes (1)

• Change in Lower Extremity Function

  The Lower Extremity Function Scale (LEFS) consists of 20 items, on an adjectival scale, that assess difficulty during mobility tasks ranging from transfers to running. Each item is scored from 0 (extreme difficulty or unable to perform activity), to 4 (no difficulty to perform activity). The minimum possible score is 0, and the maximum possible score is 80. Scores closer to 80 represent better self-reported physical function. It is reliable and valid in knee OA and has superior sensitivity to change compared to similar measures.

  Week 1 and Week 13

Secondary Outcomes (14)

• Change in Self-reported Knee and Hip Pain

  Week 1 and Week 13

• Change in Resilience

  Week 1 and Week 13

• Change in Mobility Performance (Six-Minute Walk Test)

  Week 1 and Week 13

• Change in Mobility Performance (40 Metre Walk Test)

  Week 1 and Week 13

• Change in Mobility Performance (Stair Ascent)

  Week 1 and Week 13

Study Arms (2)

Exercise

EXPERIMENTAL

The participants in this arm were asked to attend 3 group classes per week for 12 weeks taught by a certified exercise instructor. Four class times were offered per week. These classes included a warm-up, static poses shown to decrease knee joint loading, and a cool down including flexibility exercises. Measurements were obtained at baseline (before intervention) and at follow-up (following intervention). Outcomes included clinical mobility; pain; isometric leg strength; cardiovascular fitness; and resilience.

Other: Exercise

No Exercise

OTHER

The participants in this arm were asked to refrain from changing their physical activity over the 12 weeks and maintain any strategies typically used to manage knee and/or hip pain. Since it is known that exercise is beneficial for pain management and strengthening in knee OA, participants randomized to the no exercise group were offered a free exercise pass following completion of the study. Measurements were obtained at baseline (before intervention) and at follow-up (following intervention). Outcomes included clinical mobility; pain; isometric leg strength; cardiovascular fitness; and resilience.

Other: No Exercise

Interventions

Exercise OTHER

A biomechanical exercise program shown to decrease joint loading was administered 3 times a week for 12 weeks. Outcomes included mobility performance; pain; strength; cardiovascular fitness; and resilience.

Exercise

No Exercise OTHER

A no exercise (control) group maintained their existing activity level for 12 weeks. Outcomes included mobility performance; pain; strength; cardiovascular fitness; and resilience.

No Exercise

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age or older
• McMaster employee
• Sedentary job (stand or walk for \<1/3 of work day)
• Able to safely climb two flights of stairs
• Hip pain
• Hip pain during internal rotation and hip flexion
• Knee pain
• Less than 30 minutes of morning stiffness in the knee
• Crepitus in the knee with active range of motion
• Bony enlargement around the knee
• Bony tenderness to palpation at the knee
• No warmth around the knee

You may not qualify if:

• Any other forms of arthritis
• Osteoporosis-related fracture
• History of patellofemoral symptoms
• Active non-arthritic hip or knee disease
• Hip or knee surgery
• Use of cane or walking aid
• Unstable heart condition
• Neurological conditions
• Hip, knee or ankle injuries in past 3 months
• Physician-advised restriction to physical activity
• Any injuries that would prohibit participation in exercise
• Ipsilateral ankle conditions
• Currently receiving cancer treatment
• Currently pregnant

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

McMaster University

Hamilton, Ontario, L8P 3Y4, Canada

Location

Related Publications (1)

• Chopp-Hurley JN, Brenneman EC, Wiebenga EG, Bulbrook B, Keir PJ, Maly MR. Randomized Controlled Trial Investigating the Role of Exercise in the Workplace to Improve Work Ability, Performance, and Patient-Reported Symptoms Among Older Workers With Osteoarthritis. J Occup Environ Med. 2017 Jun;59(6):550-556. doi: 10.1097/JOM.0000000000001020.

  PMID: 28379878 DERIVED

MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Limitations and Caveats

* Sample size in this trial was limited * Adherence to the exercise classes in the exercise group was poor

Results Point of Contact

• Title: Dr. Monica Maly
• Organization: McMaster University/University of Waterloo

mrmaly@uwaterloo.ca

519-888-4567

Study Officials

• Monica R Maly, PT, PhD

  McMaster University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2015
• First Posted: November 20, 2015
• Study Start: August 1, 2015
• Primary Completion: July 1, 2016
• Study Completion: July 1, 2016
• Last Updated: March 22, 2018
• Results First Posted: March 10, 2017

Record last verified: 2017-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)