Improving Resilience and Longevity for Workers Through Exercise

NCT03050320 | Completed Results DMC

• 1 other identifier: Workplace Exercise
• Study Type: interventional
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine the impact of an OA-specific aerobic and strengthening exercise program, delivered within the workplace, on mobility, pain, physical capacity, and resilience among workers with knee or hip OA as well as those with no joint pain. The investigators hypothesize that exercise designed for OA, delivered at work, will improve all of these outcomes.

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip

Keywords

Resilience; Exercise in the workplace

Outcome Measures

Primary Outcomes (1)

• Change in Lower Extremity Functional Scale

  The Lower Extremity Function Scale (LEFS) consists of 20 items, on an adjectival scale, that assess difficulty during mobility tasks ranging from transfers to running. Each item is scored from 0 (extreme difficulty or unable to perform activity), to 4 (no difficulty to perform activity). The minimum possible score is 0, and the maximum possible score is 80. Scores closer to 80 represent better self-reported physical function. It is reliable and valid in knee OA and has superior sensitivity to change compared to similar measures

  Weeks 1 and 13

Secondary Outcomes (12)

• Change in Self-reported Knee and Hip Pain

  Weeks 1 and 13

• Change in Self-reported Upper Extremity Pain

  Weeks 1 and 13

• Change in Isometric Knee Extensor and Flexor Strength

  Weeks 1 and 13

• Change in Grip Strength

  Weeks 1 and 13

• Change in Cardiovascular Fitness

  Weeks 1 and 13

Study Arms (2)

Exercise

EXPERIMENTAL

The participants in this arm will be asked to attend 3 group classes per week for 12 weeks taught by a certified exercise instructor. Five class times will be offered per week. These classes included a warm-up, static poses shown to decrease knee joint loading, and a cool down including flexibility exercises. Measurements will be obtained at baseline (before intervention) and at follow-up (following intervention). Outcomes included clinical mobility; pain; isometric leg strength; cardiovascular fitness; and resilience.

Other: Exercise

No Exercise

OTHER

The participants in this arm will be asked to refrain from changing their physical activity over the 12 weeks and maintain any strategies typically used to manage knee and/or hip pain. Since it is known that exercise is beneficial for pain management and strengthening in knee OA, participants randomized to the no exercise group will be offered the same exercise program following completion of the study. Measurements will be obtained at baseline (before intervention) and at follow-up (following intervention). Outcomes included clinical mobility; pain; isometric leg strength; cardiovascular fitness; and resilience.

Other: No Exercise

Interventions

Exercise OTHER

A biomechanical exercise program shown to decrease joint loading will be administered 3 times a week for 12 weeks. Outcomes included mobility performance; pain; strength; cardiovascular fitness; and resilience.

Exercise

No Exercise OTHER

A no exercise (control) group will be asked to maintain their existing activity level for 12 weeks. Outcomes included mobility performance; pain; strength; cardiovascular fitness; and resilience.

No Exercise

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• full-time or part-time administrative employees

You may not qualify if:

• Any other forms of arthritis
• Osteoporosis-related fracture
• History of patellofemoral symptoms
• Active non-arthritic hip or knee disease
• Hip or knee surgery
• Use of cane or walking aid
• Unstable heart condition
• Neurological conditions
• Hip, knee or ankle injuries in past 3 months
• Physician-advised restriction to physical activity
• Any injuries that would prohibit participation in exercise
• Ipsilateral ankle conditions
• Currently receiving cancer treatment
• Currently pregnant

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

McMaster University

Hamilton, Ontario, L8S4L8, Canada

Location

Related Publications (1)

• Mulla DM, Wiebenga EG, Chopp-Hurley JN, Kaip L, Jarvis RS, Stephens A, Keir PJ, Maly MR. The Effects of Lower Extremity Strengthening Delivered in the Workplace on Physical Function and Work-Related Outcomes Among Desk-Based Workers: A Randomized Controlled Trial. J Occup Environ Med. 2018 Nov;60(11):1005-1014. doi: 10.1097/JOM.0000000000001408.

  PMID: 30020219 DERIVED

MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip

Interventions

Exercise

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Limitations and Caveats

* a limited number of participants were recruited due to time and space limitations within the exercise facility * physical activity levels of the control group during the 12-week intervention period were not quantified

Results Point of Contact

• Title: Dr. Monica Maly
• Organization: McMaster University/University of Waterloo

mrmaly@uwaterloo.ca

519-888-4567

Study Officials

• Monica R Maly, PT, PhD

  McMaster University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 8, 2017
• First Posted: February 10, 2017
• Study Start: February 8, 2017
• Primary Completion: June 30, 2017
• Study Completion: June 30, 2017
• Last Updated: August 10, 2018
• Results First Posted: August 10, 2018

Record last verified: 2017-11

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)