NCT03302104

Brief Summary

In our study, we used data from 4,758 healthy adults from the 1999-2002 National Health and Nutrition Examination Surveys to examine the associations between evidence-based diet quality indices and leukocyte telomere length. Our study assessed the four most widely recognized and commonly used diet quality indices in nutritional epidemiology: the USDA-developed Healthy Eating Index-2010, the Alternate Healthy Eating Index-2010, the Mediterranean Diet Score, and the DASH diet score. Analyses were adjusted for sociodemographic and health variables known to influence dietary intake and cellular aging.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,758

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 1999

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1999

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2002

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2002

Completed
14.7 years until next milestone

First Submitted

Initial submission to the registry

September 22, 2017

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 4, 2017

Completed
Last Updated

October 4, 2017

Status Verified

September 1, 2017

Enrollment Period

4 years

First QC Date

September 22, 2017

Last Update Submit

September 29, 2017

Conditions

Telomere Length, Mean LeukocyteDiet Habit

Outcome Measures

Primary Outcomes (1)

  • Leukocyte telomere length

    1999-2002

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study population was comprised of 4,758 healthy adults, aged 20 to 65 years, who had complete dietary and leukocyte telomere length (LTL) data measured in 1999-2002 National Health and Nutrition Examination Surveys (NHANES), without a prior diagnosis of major chronic disease (coronary heart disease, angina, myocardial infarction, stroke, diabetes, congestive heart failure, and cancer).

You may qualify if:

  • Ages 20 to 65 years
  • No prior diagnosis of major chronic disease (coronary heart disease, angina, myocardial infarction, stroke, diabetes, congestive heart failure, and cancer)

You may not qualify if:

  • Prior diagnosis of major chronic disease (coronary heart disease, angina, myocardial infarction, stroke, diabetes, congestive heart failure, and cancer)
  • Younger than age 20 or older than age 65

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Feeding Behavior

Condition Hierarchy (Ancestors)

Behavior, AnimalBehavior

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 22, 2017

First Posted

October 4, 2017

Study Start

January 1, 1999

Primary Completion

December 31, 2002

Study Completion

December 31, 2002

Last Updated

October 4, 2017

Record last verified: 2017-09