Epidemiology of Sepsis in Turkish ICUs.

NCT03249246 | Completed DMC

• 1 other identifier: TurkishICS
• Study Type: observational
• Target: 1,499
• Locations: 0 countries
• Sites: N/A

Brief Summary

The prevalence and mortality of sepsis in Turkey is not know at large. Turkish Society of Intensive Care Medicine, Sepsis Study Group conducted a multi-centre,point prevalence survey to determine the prevalence, causative micro-organisms and outcome of sepsis in Turkish ICUs.

Conditions

Sepsis; Septic Shock; Severe Sepsis

Keywords

Sepsis; ICU; Point prevalence

Outcome Measures

Primary Outcomes (1)

• Prevalence of sepsis

  The prevalence of sepsis,Severe sepsis and septic shock on study day

  Up to 12 weeks.

Secondary Outcomes (1)

• Mortality rate of sepsis

  Mortality at 30 days

Study Arms (4)

Infection only

The patients have only infection

Other: No intervention

Infection + SIRS

Patients have infection plus systemic inflammatory response syndrome (SIRS)

Other: No intervention

Severe sepsis

Septic patients with newly developed organ dysfunctions

Other: No intervention

Septic shock

Sepsis plus sepsis related hypotension

Other: No intervention

Interventions

No intervention OTHER

Infection + SIRS; Infection only; Septic shock; Severe sepsis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients (\>18 yr)present on the participating ICU or admitted to participating ICUs on study day

You may not qualify if:

• Age\<18 years
• Patients who underwent cardiovascular surgery.

Sponsors & Collaborators

• Nur Baykara: lead
• Turkish Society of Intensive Care, Sepsis Study Group: collaborator

Related Publications (4)

• Rhodes A, Phillips G, Beale R, Cecconi M, Chiche JD, De Backer D, Divatia J, Du B, Evans L, Ferrer R, Girardis M, Koulenti D, Machado F, Simpson SQ, Tan CC, Wittebole X, Levy M. The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study). Intensive Care Med. 2015 Sep;41(9):1620-8. doi: 10.1007/s00134-015-3906-y. Epub 2015 Jun 25.

  PMID: 26109396 BACKGROUND

• Falagas ME, Rafailidis PI, Kofteridis D, Virtzili S, Chelvatzoglou FC, Papaioannou V, Maraki S, Samonis G, Michalopoulos A. Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study. J Antimicrob Chemother. 2007 Nov;60(5):1124-30. doi: 10.1093/jac/dkm356. Epub 2007 Sep 20.

  PMID: 17884829 BACKGROUND

• Fleischmann C, Scherag A, Adhikari NK, Hartog CS, Tsaganos T, Schlattmann P, Angus DC, Reinhart K; International Forum of Acute Care Trialists. Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations. Am J Respir Crit Care Med. 2016 Feb 1;193(3):259-72. doi: 10.1164/rccm.201504-0781OC.

  PMID: 26414292 RESULT

• Baykara N, Akalin H, Arslantas MK, Hanci V, Caglayan C, Kahveci F, Demirag K, Baydemir C, Unal N; Sepsis Study Group. Epidemiology of sepsis in intensive care units in Turkey: a multicenter, point-prevalence study. Crit Care. 2018 Apr 16;22(1):93. doi: 10.1186/s13054-018-2013-1.

  PMID: 29656714 DERIVED

MeSH Terms

Conditions

Sepsis; Shock, Septic

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Shock

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Prof.Dr.Nur Baykara

Study Record Dates

• First Submitted: August 9, 2017
• First Posted: August 15, 2017
• Study Start: January 27, 2016
• Primary Completion: January 28, 2016
• Study Completion: February 27, 2016
• Last Updated: August 15, 2017

Record last verified: 2017-08

Data Sharing

• IPD Sharing: Will not share