Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

49 trials with published results (6%)

Research Maturity

394 completed trials (48% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

6.6%

54 terminated out of 821 trials

Success Rate

87.9%

+1.4% vs benchmark

Late-Stage Pipeline

18%

148 trials in Phase 3/4

Results Transparency

12%

49 of 394 completed with results

Key Signals

49 with results88% success54 terminated

Data Visualizations

Phase Distribution

514Total
Not Applicable (233)
Early P 1 (2)
P 1 (31)
P 2 (100)
P 3 (78)
P 4 (70)

Trial Status

Completed394
Unknown175
Recruiting95
Not Yet Recruiting62
Terminated54
Withdrawn21

Trial Success Rate

87.9%

Benchmark: 86.5%

Based on 394 completed trials

Clinical Trials (821)

Showing 20 of 20 trials
NCT07735741Not Yet Recruiting

Immune Dysregulation During Sepsis: A Natural History Cohort

NCT06363149CompletedPrimary

Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients

NCT06746753Phase 4Not Yet RecruitingPrimary

Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic Shock

NCT07721974Not ApplicableNot Yet RecruitingPrimary

Alterations of the Renin-angiotensin-aldosterone System in sEptic Shock

NCT07716956Not ApplicableNot Yet RecruitingPrimary

Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients

NCT07530146Phase 3Recruiting

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation

NCT07711197Not ApplicableNot Yet RecruitingPrimary

Effects of Hemoadsorption on Vascular Integrity in Septic Shock

NCT07703592Not Yet RecruitingPrimary

Comparison of Manual PAOP and Automatic PAOP (Smart Wedge)

NCT05148286Phase 4RecruitingPrimary

Albumin and Crystalloid Administration in Septic Shock

NCT07388628Recruiting

ARTICE® Real Data Collection & Observational Trial, Phase 4 Study

NCT07698834Not Yet RecruitingPrimary

Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound

NCT04067674RecruitingPrimary

Septic Shock-induced Immunosuppression

NCT07695337Phase 4CompletedPrimary

Continuous Infusion Versus Intermittent Bolus Hydrocortisone in Septic Shock

NCT07483710Not ApplicableRecruitingPrimary

Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months Mortality After ICU Discharge for Patients Admitted for Septic Shock. The SIMS Study

NCT07685002Not Yet RecruitingPrimary

Characterizing Perfusion and Congestion Responses to Fluid Loading in Critically Ill Septic Patients

NCT07682766RecruitingPrimary

BioMArkeRs of INflammation, Infection, and Immunity in the Critical Area (MARINA): the Use of Inflammatory and Immunity Biomarkers as Early Predictors of Clinical Severity, Organ Damage, Response to Treatment, and Infectious Complications in Patients Admitted to the Critical Care Area.

NCT05824767Phase 4CompletedPrimary

Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock

NCT07661303Not ApplicableNot Yet RecruitingPrimary

Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety Evaluation

NCT07313670Not ApplicableCompletedPrimary

Outcome of Using Hydrocortisone in Early Treatment of Pediatric Septic Shock

NCT03472079CompletedPrimary

TIMP2*IGFBP7 and Transient AKI

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