Registration of Sepsis Patients in the Emergency Department

NCT06068192 | Not Yet Recruiting

• 1 other identifier: RSP
• Study Type: observational
• Target: 500
• Locations: 0 countries
• Sites: N/A

Brief Summary

1\) Establish a clinical data database for sepsis patients in the Emergency Department of the First Hospital of Jilin University. Describe the clinical data and prognosis of patients with simple systemic inflammatory response syndrome (common infection), pre sepsis, sepsis, and septic shock. 2) Explore the risk factors related to the progression of sepsis in patients in the early stages, as well as the risk factors related to the patient's prognosis. 3) Analyze the risk factors related to the prognosis of sepsis patients, and provide clinical basis for the treatment and long-term prognosis of sepsis patients. 4) Search for diagnostic biomarkers and prognostic serum biomarkers for patients with sepsis, sepsis, and septic shock.

Conditions

Sepsis

Outcome Measures

Primary Outcomes (2)

• The patient dies within 28 days after hospitalization

  The patient dies within 28 days after hospitalization

  within 28 days after hospitalization

• The patient does not die within 28 days after hospitalization

  The patient does not die within 28 days after hospitalization

  within 28 days after hospitalization

Study Arms (2)

28th day death group

Patient dies within 28 days after hospitalization

Other: no intervention

non-28th day death group

The patient does not die within 28 days after hospitalization

Other: no intervention

Interventions

no intervention OTHER

no intervention

28th day death group; non-28th day death group

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study site and population included patients with systemic inflammatory response syndrome caused by "infectious factors" who were admitted to the Emergency Department of the First Hospital of Jilin University from January 1, 2023 to December 31, 2027. The screening criteria for the study population were patients with "systemic inflammatory response syndrome" caused by sensory factors who were continuously registered and treated at the Emergency Department of the First Affiliated Hospital of Jilin University from January 1, 2023 to December 31, 2027.

You may qualify if:

• Age greater than or equal to 15 years old; 2) A patient who sought medical treatment at the Emergency Department of Jilin University First Hospital due to "systemic inflammatory response syndrome" (see relevant concepts and definitions in section 4.2 below). 3) Within 24 hours of seeking medical attention, evidence of "infection" can be clearly detected through imaging and laboratory examinations. Patients can be diagnosed and classified as at least one of the following conditions: respiratory system infection, digestive system infection, urinary system infection, blood borne infection, or skin soft tissue infection.

You may not qualify if:

• pregnant and lactating women; 2) Active pulmonary tuberculosis; 3) Patients who do not agree to participate in this study.

Sponsors & Collaborators

• The First Hospital of Jilin University: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

blood,urine and other infection sites to detect the pathogen.

MeSH Terms

Conditions

Sepsis

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 28, 2023
• First Posted: October 5, 2023
• Study Start: January 1, 2024
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: October 26, 2023

Record last verified: 2023-09