Key Insights

Highlights

Success Rate

83% trial completion

Published Results

20 trials with published results (10%)

Research Maturity

121 completed trials (63% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

12.4%

24 terminated out of 193 trials

Success Rate

83.4%

-3.1% vs benchmark

Late-Stage Pipeline

19%

37 trials in Phase 3/4

Results Transparency

17%

20 of 121 completed with results

Key Signals

20 with results83% success24 terminated

Data Visualizations

Phase Distribution

116Total
Not Applicable (48)
P 1 (5)
P 2 (26)
P 3 (21)
P 4 (16)

Trial Status

Completed121
Unknown33
Terminated24
Withdrawn7
Recruiting2
Not Yet Recruiting2

Trial Success Rate

83.4%

Benchmark: 86.5%

Based on 121 completed trials

Clinical Trials (193)

Showing 20 of 20 trials
NCT05413343Active Not RecruitingPrimary

Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

NCT07706413Not ApplicableNot Yet RecruitingPrimary

Plasma Exchange in Children With Severe Sepsis and Septic Shock

NCT03115125Not ApplicableTerminatedPrimary

Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe Sepsis

NCT01162109Phase 1CompletedPrimary

Zinc Therapy in Critical Illness

NCT02361528Phase 3Completed

GM-CSF to Decrease ICU Acquired Infections

NCT05296590Active Not Recruiting

Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia

NCT01626612Phase 3CompletedPrimary

De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis

NCT04955210Recruiting

A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children

NCT02664753Phase 3TerminatedPrimary

L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury

NCT01315782Not Yet Recruiting

Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

NCT00793442Completed

Endothelium in Severe Sepsis

NCT03895853Phase 2Terminated

Early Metabolic Resuscitation for Septic Shock

NCT06143137RecruitingPrimary

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up

NCT05304728Enrolling By InvitationPrimary

Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol

NCT01371929Terminated

Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis Study

NCT02777606Not ApplicableCompletedPrimary

The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis

NCT05665153UnknownPrimary

Symphony IL-6 Study in Patients at Risk of Severe Sepsis

NCT02041663Not ApplicableCompleted

Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis

NCT05060250UnknownPrimary

Symphony IL-6 Cutoff Establishment Study for Patients at Risk of Severe Sepsis Due to COVID-19

NCT05048927UnknownPrimary

Symphony IL-6 Cutoff Validation Study for Patients at Risk of Severe Sepsis

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Research Network

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