Analgesic Effect of Adductor Canal Block With and Without Dexamethasone for Knee Arthroscopy
The Effect of Adding Dexamethasone to Bupivacaine in Ultrasound Guided Adductor Canal Block for Postoperative Analgesia Following Knee Arthroscopic Anterior Cruciate Ligament Reconstruction
1 other identifier
interventional
60
0 countries
N/A
Brief Summary
The purpose of this study was to evaluate the efficacy of ultra-sound guided adductor canal block with and without dexamethasone when added to bupivacaine on the duration of postoperative analgesia in patients undergoing arthroscopic anterior cruciate ligament reconstruction surgery using Numeric Rating Score (NRS).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2016
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
July 22, 2017
CompletedFirst Submitted
Initial submission to the registry
July 24, 2017
CompletedFirst Posted
Study publicly available on registry
August 4, 2017
CompletedAugust 4, 2017
August 1, 2017
8 months
July 24, 2017
August 3, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
duration of postoperative analgesia
assessed by pain score
One day postoperative
Secondary Outcomes (1)
postoperative analgesic consumption
One day postoperative
Study Arms (2)
group I
ACTIVE COMPARATORGroup I (MS): received single shot 20 ml 0.5% isobaric bupivacaine + 2.0 ml normal saline solution injected into the adductor canal preoperatively.
group II
ACTIVE COMPARATORGroup II (MD): received 20 ml 0.5% isobaric bupivacaine + 8.0 mg dexamethasone (2.0 ml) injected into adductor canal preoperatively.
Interventions
Eligibility Criteria
You may qualify if:
- Adult ASA I-II Arthroscopic anterior cruciate ligament reconstruction
You may not qualify if:
- patient refusal
- drug allergy
- failed procedure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Rasouli MR, Viscusi ER. Adductor Canal Block for Knee Surgeries: An Emerging Analgesic Technique. Arch Bone Jt Surg. 2017 May;5(3):131-132. No abstract available.
PMID: 28656158RESULTIbrahim AS, Aly MG, Farrag WS, Gad El-Rab NA, Said HG, Saad AH. Ultrasound-guided adductor canal block after arthroscopic anterior cruciate ligament reconstruction: Effect of adding dexamethasone to bupivacaine, a randomized controlled trial. Eur J Pain. 2019 Jan;23(1):135-141. doi: 10.1002/ejp.1292. Epub 2018 Aug 6.
PMID: 30066465DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor of Anesthesia
Study Record Dates
First Submitted
July 24, 2017
First Posted
August 4, 2017
Study Start
October 1, 2016
Primary Completion
June 1, 2017
Study Completion
July 22, 2017
Last Updated
August 4, 2017
Record last verified: 2017-08