Success Metrics

Clinical Success Rate
80.7%

Based on 994 completed trials

Completion Rate
81%(994/1231)
Active Trials
416(20%)
Results Posted
61%(609 trials)
Terminated
237(11%)

Phase Distribution

Ph phase_1
430
21%
Ph not_applicable
189
9%
Ph phase_2
716
35%
Ph phase_4
269
13%
Ph early_phase_1
25
1%
Ph phase_3
411
20%

Phase Distribution

455

Early Stage

716

Mid Stage

680

Late Stage

Phase Distribution2040 total trials
Early Phase 1First-in-human
25(1.2%)
Phase 1Safety & dosage
430(21.1%)
Phase 2Efficacy & side effects
716(35.1%)
Phase 3Large-scale testing
411(20.1%)
Phase 4Post-market surveillance
269(13.2%)
N/ANon-phased studies
189(9.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.6%

994 of 1333 finished

Non-Completion Rate

25.4%

339 ended early

Currently Active

416

trials recruiting

Total Trials

2,063

all time

Status Distribution
Active(481)
Completed(994)
Terminated(339)
Other(249)

Detailed Status

Completed994
unknown244
Terminated237
Recruiting232
Active, not recruiting184
Withdrawn102

Development Timeline

Analytics

Development Status

Total Trials
2063
Active
416
Success Rate
80.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 125 (1.2%)
Phase 1430 (21.1%)
Phase 2716 (35.1%)
Phase 3411 (20.1%)
Phase 4269 (13.2%)
N/A189 (9.3%)

Trials by Status

suspended50%
completed99448%
terminated23711%
enrolling_by_invitation70%
not_yet_recruiting583%
withdrawn1025%
recruiting23211%
active_not_recruiting1849%
unknown24412%

Recent Activity

Clinical Trials (2,063)

Showing 20 of 2,063 trialsScroll for more
NCT05498220Phase 2

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Terminated
NCT07095452Phase 2

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Recruiting
NCT06083922Phase 2

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

Recruiting
NCT04973605Phase 1

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Recruiting
NCT06152575Phase 3

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Recruiting
NCT05285813Phase 2

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

Active Not Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT03132454Phase 1

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Active Not Recruiting
NCT02719613Phase 2

Continuing Treatment for Participants Who Have Participated in a Prior Protocol Investigating Elotuzumab

Completed
NCT06136650Phase 3

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Recruiting
NCT07096778Phase 2

Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Recruiting
NCT03763162Phase 2

Daratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT01424982Phase 2

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT05434689Phase 1

COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide

Active Not Recruiting
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT07082270Phase 1

Selvigaltin With Standard of Care Treatment for the Treatment of Relapsed/Refractory Multiple Myeloma

Withdrawn
NCT06615479Phase 3

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Recruiting
NCT04216524Phase 2

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

Recruiting
NCT02203643Phase 2

Evaluation of the Safety and the Efficacy of Carfilzomib Combined With Cyclophosphamide and Dexamethasone (CCyd) or Lenalidomide and Dex (CRd) Followed by ASCT or 12 Cycles of Carf Combined With Dex and Len for Patients Eligible for ASCT With Newly Diagnosed Multiple Myeloma.

Completed

Drug Details

Intervention Type
DRUG
Total Trials
2,063