NCT04690894

Brief Summary

this prospective randomized double blind controlled study was conducted on 60 child scheduled for lower abdominal surgery under general anesthesia. the patients were randomly allocated into 3 parallel groups.group (ESB) patients received ultrasound-guided erector spinae block in a dose of 0.4mg/ml of 0.25%bupivacaine between the 10th transverse process and erector spinae muscles.group(CB) patients received ultrasound-guided caudal block in a dose of 2.5mg/kg of 0.25%bupivacaine. group(CO) did,t received any block

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 15, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2020

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

December 28, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 31, 2020

Completed
Last Updated

March 8, 2021

Status Verified

May 1, 2019

Enrollment Period

6 months

First QC Date

December 28, 2020

Last Update Submit

March 4, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • number of patients need rescue analgesia

    total number of patients need addition of anagesia

    24 hours

Secondary Outcomes (2)

  • First analgesic request

    24 hours

  • Hemodynamic changes in the study period

    24 hours

Study Arms (3)

Erector spinae group

ACTIVE COMPARATOR

the child received ultrasound-guided erector spinae muscle block in a dose of 0.4mg/kg of 0.25%bupivacaine between the 10th transverse process and erector spinae muscle

Procedure: erector spinae block - caudal block

caudal group

ACTIVE COMPARATOR

child received ultrasound-guided caudal block in a dose of 2.5mg/kg of bupivacaine 0.25%

Procedure: erector spinae block - caudal block

control

NO INTERVENTION

child didn't received any regional block

Interventions

the child placed in lateral position identification of spinous process of 10th thoracic vertebral then the transducer was moved 2.5 cm laterally to visualize the transverse process and a total of 0.4mg/kg of 0.25%bupivacaine was adminstered

Erector spinae groupcaudal group

Eligibility Criteria

Age2 Years - 6 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • pediatric patients aged 2-6 years scheduled for lower abdominal surgery under general anesthesia

You may not qualify if:

  • parent refusal
  • spinal and meningeal anomalies
  • mental retardation
  • blood disease
  • infection at site of injection
  • drug allergy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Medicine

Minya, 61111, Egypt

Location

Related Publications (1)

  • Abdelrazik AN, Ibrahim IT, Farghaly AE, Mohamed SR. Ultrasound-guided Erector Spinae Muscle Block Versus Ultrasound-guided Caudal Block in Pediatric Patients Undergoing Lower Abdominal Surgeries. Pain Physician. 2022 Jul;25(4):E571-E580.

Study Officials

  • Ibrahim Talaat, MD

    professor

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer

Study Record Dates

First Submitted

December 28, 2020

First Posted

December 31, 2020

Study Start

July 15, 2019

Primary Completion

January 15, 2020

Study Completion

February 15, 2020

Last Updated

March 8, 2021

Record last verified: 2019-05

Locations