NCT03134599

Brief Summary

The purpose of this study is to evaluate the clinical performance and subject's preference out of three LRE (Limbal Ring Enhancing) lens types: etafilcon A (Johnson\&Johnson), methafilcon A (Interozzo), and methafilcon A (CooperVision).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 26, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 1, 2017

Completed
22 days until next milestone

Study Start

First participant enrolled

May 23, 2017

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 24, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 24, 2017

Completed
1.7 years until next milestone

Results Posted

Study results publicly available

February 22, 2019

Completed
Last Updated

December 19, 2019

Status Verified

December 1, 2019

Enrollment Period

1 month

First QC Date

April 26, 2017

Results QC Date

July 26, 2018

Last Update Submit

December 10, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Comfort

    Subjective ratings of comfort for each lens pair was assessed. Scale 0-100, 0=causes pain, 100=very comfortable.

    1 week per intervention

Study Arms (3)

etafilcon A

ACTIVE COMPARATOR
Device: etafilcon A

methafilcon A - Interozzo

ACTIVE COMPARATOR
Device: methafilcon A - Interozzo

methafilcon A - CVI

ACTIVE COMPARATOR
Device: methafilcon A - CVI (CooperVision)

Interventions

contact lens

etafilcon A

contact lens

methafilcon A - Interozzo

contact lens

methafilcon A - CVI

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age of 18 years and above and has full legal capacity as a volunteer Understand the rights as a research subject and willing and able sign a statement of informed consent
  • Existing soft contact lens wearers or previous experience of contact lens wear
  • Being able to wear the study lenses for at least eight hours a day
  • At least 6/9 visual acuity in each eye with the study lenses
  • Astigmatism less than 1.50 D (Diopter) in both eyes
  • Agreed to follow the protocol and not to participate in other clinical research for the duration of this study

You may not qualify if:

  • Have an ocular disorder which would normally contraindicate contact lens wear
  • Have a systemic disorder or any infectious diseases which would normally contraindicate contact lens wear
  • Have previously had any ocular surgery such as corneal refractive surgery
  • Have less than 6/9 visual acuity in each eye with the study lenses
  • Are currently using any topical medication such as eye drops or ointment
  • Have any corneal distortion resulting from previous rigid lens wear or have keratoconus
  • Are currently pregnant or lactating
  • No previous contact lens wear

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Optometry & Vision Science, Catholic University of Daegu, Korea (Rep)

Daegu, South Korea

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Jose Vega, O.D., MSc., FAAO
Organization
CooperVision

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 26, 2017

First Posted

May 1, 2017

Study Start

May 23, 2017

Primary Completion

June 24, 2017

Study Completion

June 24, 2017

Last Updated

December 19, 2019

Results First Posted

February 22, 2019

Record last verified: 2019-12

Data Sharing

IPD Sharing
Will not share

Locations