Key Insights

Highlights

Success Rate

97% trial completion (above average)

Treatment Research

20 treatments under study, led by Atropine

Published Results

310 trials with published results (33%)

Research Leaders

20 sponsors active, led by CooperVision, Inc.

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

2.2%

21 terminated out of 951 trials

Success Rate

96.6%

+10.0% vs benchmark

Late-Stage Pipeline

9%

81 trials in Phase 3/4

Results Transparency

52%

310 of 591 completed with results

Key Signals

310 with results97% success21 terminated

Data Visualizations

Phase Distribution

781Total
Not Applicable (656)
Early Phase 1 (3)
Phase 1 (17)
Phase 1/2 (6)
Phase 2 (15)
Phase 2/3 (3)
Phase 3 (39)
Phase 4 (42)

Trial Status

Completed591
Unknown123
Recruiting82
Active Not Recruiting54
Not Yet Recruiting54
Terminated21

Trial Success Rate

96.6%

Benchmark: 86.6%

Based on 591 completed trials

Clinical Trials (951)

Showing 20 of 20 trials
NCT07889752CompletedPrimary

VEP for Assessment SMILE Visual Quality

NCT07906327Not Yet RecruitingPrimary

Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE

NCT07186088Not ApplicableEnrolling By InvitationPrimary

Therapeutic Efficacy of Different Repeated Low-Intensity Red Light Devices and Different Usage Frequencies

NCT01682434Not ApplicableWithdrawnPrimary

Wavefront-guided LASIK for Correction of Myopia

NCT07095894Phase 3RecruitingPrimary

A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

NCT07751172Not ApplicableRecruitingPrimary

Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter

NCT07129798Not ApplicableCompleted

Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent

NCT05588362Not ApplicableTerminatedPrimary

Access to EyeGlasses for School-aged Children

NCT06598423Not ApplicableRecruitingPrimary

Wavelength Intervention for Nearsighted Kids

NCT04632784Not ApplicableActive Not Recruiting

Clinical Trial With Artiflex Presbyopic (Artiplus)

NCT05689567Not ApplicableCompleted

Focus-out Glasses on Emmetropization in Chinese Children

NCT05534022Not ApplicableCompletedPrimary

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.

NCT07863713Phase 2Not Yet RecruitingPrimary

Early Intervention for High Risk Premyopic Children

NCT06743594Completed

Measurement of Antioxidant Activity and Oxidative Stress in Patients Undergoing Ophthalmic Surgery.

NCT07084844CompletedPrimary

Patient Reported Outcomes With WaveLight Plus LASIK

NCT07854457Not ApplicableNot Yet RecruitingPrimary

Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial

NCT07855094Not ApplicableActive Not RecruitingPrimary

Wavelight Plus Sightmap-LASIK vs. Wavefront-Optimized-LASIK

NCT07851532RecruitingPrimary

Screening for Hyperopic Reserve in Kindergarten

NCT07845721Not ApplicableNot Yet RecruitingPrimary

Using Contact Lenses and Spectacle Lenses as Myopia Interventions.

NCT07846787Not ApplicableNot Yet RecruitingPrimary

Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops

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Research Network

Common Treatments

  • Atropine29
  • Etafilcon A20
  • Comfilcon A12
  • Lasik11
  • Nelfilcon A Contact Lens11

Active Sponsors

  • CooperVision, Inc.101
  • Alcon Research82
  • Johnson & Johnson Vision Care, Inc.45
  • CIBA VISION38
  • Bausch & Lomb Incorporated36

Top Investigators

Related Conditions

  • Astigmatism109
  • Hyperopia82
  • Refractive Errors40
  • Refractive Error28
  • Presbyopia28

Activity Timeline