Chronic Effects Using Light-Emitting Diode Therapy (LEDT) During a Resistance Exercise Protocol for Asthmatic Patients

NCT03112239 | Completed DMC

• 1 other identifier: ERAMG-LED-PL-01
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to evaluate the effects of LED phototherapy associated with a resistance training protocol on the peripheral muscle function of moderate to severe asthmatic patients ..

Conditions

Resistance Training

Keywords

Asthma; Photobiomodulation; Resistance Training

Outcome Measures

Primary Outcomes (6)

• Pectoral Muscular Strength by 1RM.

  Muscle strength will be assessed in the pectoral muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

• Major Dorsal Muscular Strength by 1RM

  Muscle strength will be assessed in the major dorsal muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

• Femoral Quadriceps Muscular Strength by 1RM

  Muscle strength will be assessed in the femoral quadriceps muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

• Brachial Triceps Muscular Strength by 1RM

  Muscle strength will be assessed in the brachial triceps muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

• Brachial Biceps Muscular Strength by 1RM

  Muscle strength will be assessed in the brachial biceps muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

• Tibial Ischia Muscular Strength by 1RM

  Muscle strength will be assessed in the tibial ischia muscle group, using the maximal repetition (1RM) test to quantify the resistance training load (between 60 and 80%).

  Change from Baseline Peripheral muscular Strength up to 24 weeks.

Secondary Outcomes (2)

• Functional Capacity by Cardiopulmonary exercise test.

  Change from baseline measured by cardiopulmonary exercise test up to 24 weeks.

• Functional Capacity by Incremental Shuytle Walk Test.

  Change from baseline measured by Incremental Shuttle Walk Test distance up to 24 weeks.

Study Arms (2)

photobiomodulation by active LEDT

ACTIVE COMPARATOR

The subjects will be initially pre-evaluated by performing pulmonary function tests, peripheral muscle strength tests, functional capacity tests, physical activity questionnaires and clinical control of asthma, and cardiopulmonary exercise test. After the evaluation, patients will be randomized into two resistance training groups, one of them being associated to the intervention with active photobiomodulation by LEDT to increase peripheral muscle function post resistance training.

Device: Light-Emitting Diode Therapy (LEDT)

photobiomodulation by Placebo LEDT

PLACEBO COMPARATOR

The subjects will be initially pre-evaluated by performing pulmonary function tests, peripheral muscle strength tests, functional capacity tests, physical activity questionnaires and clinical control of asthma, and cardiopulmonary exercise test. After the evaluation, patients will be randomized into two resistance training groups, one of them being associated to the intervention with placebo LEDT photobiomodulation to increase peripheral muscle function post resistance training.

Device: Light-Emitting Diode Therapy (LEDT)

Interventions

Light-Emitting Diode Therapy (LEDT) DEVICE

Light-emitting diode, has effects similar to the photobiomodulation by low-level laser intensity.

Also known as: photobiomodulation by LEDT

photobiomodulation by Placebo LEDT; photobiomodulation by active LEDT

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with a medical outpatient setting less than six months; With a stable clinical picture during three months, ie without exacerbations and with optimized drug therapy.
• Signed an informed consent form (TCLE) accepting participation in the research.

You may not qualify if:

• Diagnosis of heart disease associated with lung disease, musculoskeletal disease that may interfere with assessment or exercise, pulmonary hypertension, calcium absorption deficiency, BMI ≥ 30, or difficulty learning.

Sponsors & Collaborators

• University of Nove de Julho: lead
• Fabiano Politti: collaborator
• LUCIANA MARIA MALOSA SAMPAIO: collaborator

Study Sites (1)

Ivan Peres Costa

São Paulo, São Paulo, 05415-012, Brazil

Location

Related Publications (2)

• Miranda EF, Leal-Junior EC, Marchetti PH, Dal Corso S. Acute effects of light emitting diodes therapy (LEDT) in muscle function during isometric exercise in patients with chronic obstructive pulmonary disease: preliminary results of a randomized controlled trial. Lasers Med Sci. 2014 Jan;29(1):359-65. doi: 10.1007/s10103-013-1359-5. Epub 2013 Jun 7.

  PMID: 23743817 BACKGROUND

• Dourado VZ, Tanni SE, Antunes LC, Paiva SA, Campana AO, Renno AC, Godoy I. Effect of three exercise programs on patients with chronic obstructive pulmonary disease. Braz J Med Biol Res. 2009 Mar;42(3):263-71. doi: 10.1590/s0100-879x2009000300007.

  PMID: 19287905 RESULT

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Luciana MM Sampaio, PhD

  University of Nove de Julho

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physitherapist, Master and PhD student

Study Record Dates

• First Submitted: December 3, 2016
• First Posted: April 13, 2017
• Study Start: March 1, 2014
• Primary Completion: January 1, 2015
• Study Completion: December 1, 2016
• Last Updated: April 13, 2017

Record last verified: 2017-04

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)