Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

NCT06413199 | Recruiting

• 1 other identifier: PSRDHospital
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The novelty of this study is to identify the mechanism of nervous system by applying resistance training intervention in healthy individuals.

Conditions

Resistance Training

Keywords

Resistance Training; Performance; Nervous Response; Muscle growth; Exercise Induced Performance

Outcome Measures

Primary Outcomes (4)

• NCS (Motor Nerve Conduction Study)

  To determine how fast or slow the nerves are conducting an electrical current using F wave

  • 0 week • 8th week

• EEG (Electroencephalography)

  To measure the electrical activity of the brain using alpha and beta waves

  • 0 week • 8th week

• Dynamometer

  To measure the strength after resistance training

  • 0 week • 4th week • 8th week

• Estimation of Albumin & Globulin ratio

  To measure the total amount of protein in blood and effects of resistance training

  • 0 week • 8th week

Study Arms (2)

Hyper Training Group

EXPERIMENTAL

2 training session per week for 2 months, 1 set of 10 unloaded repetitions in arms as a warm-up, 4 sets with a goal of 8-12 repetitions with 90 seconds of rest between sets and elbows had to be fully locked out to be counted as a repetition, 1.5 seconds for concentric and 1.5 seconds for eccentric portion.

Other: Hyper Training

1 Repetition Maximum Group

ACTIVE COMPARATOR

2 training session per week for 2 months, 1 set of 10 unloaded repetitions in arms as a warm-up, training protocol consisted of 5 attempts to lift as much weight as possible one time for that training visit with 90 seconds of rest between attempts. The load was progressively increased each attempt to try to reach or exceed their previous 1RM.

Other: 1 Repetition maximum training group

Interventions

Hyper Training OTHER

Experimental group will perform 2 training session per week for 2 months, 1 set of 10 unloaded repetitions in arms as a warm-up, 4 sets with a goal of 8-12 Reps with 90 seconds rest between sets. 1.5 second concentric and 1.5 second eccentric contraction of bench press, The elbows had to be fully locked out to be counted as a repetition.

Hyper Training Group

1 Repetition maximum training group OTHER

2 training session per week for 8 weeks, 1 set of 10 unloaded repetitions in arms as a warm-up, 1 Repetition maximum training group consisted of 5 attempts to lift as much weight as possible one time for that training visit with 90 seconds of rest between attempts, the load was progressively increased each attempt to try to reach or exceed their previous 1 repetition maximum.

1 Repetition Maximum Group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Body Mass Index should be 18.5-24.9 kg/m2.
• Participants were untrained and had not engaged in resistance exercise within 6 months prior to beginning the study.

You may not qualify if:

• Participants with any kind of Gastrointestinal Tract disturbance will be excluded from the study.
• Participants with any kind of Musculoskeletal injury will be excluded from the study.
• Participant with any kind of Neurological disturbance will be excluded from the study.
• Participants who use tobacco products within the previous 6 months.
• Participants who take any type of medication within the previous 6 months.

Sponsors & Collaborators

• Pakistan Society for Rehabilitation of Differently Abled Hospital: lead
• University of Karachi: collaborator

Study Sites (1)

PSRD Hospital

Lahore, Punjab Province, 54000, Pakistan

RECRUITING

Related Publications (22)

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Study Officials

• Danish Latif, PhD*

  PSRD College of Rehabilitation Sciences

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Faheem Afzal, PhD*

CONTACT

00923336966697; faheem78601@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 31, 2023
• First Posted: May 14, 2024
• Study Start: August 18, 2023
• Primary Completion: December 29, 2024
• Study Completion: December 31, 2024
• Last Updated: May 14, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)