NCT02967263

Brief Summary

  • To investigate the etiology and epidemiology of acute kidney injury (AKI).
  • To find out risk factors associated with the occurence of AKI.
  • To find out risk factors related to the prognosis of AKI,focusing on uremic toxins, inflammation, oxidative stress and nutritional status.
  • To study on the relationship between gene polymorphism and prognosis of acute kidney injury.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
713

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

November 16, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 18, 2016

Completed
7.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2024

Completed
Last Updated

November 28, 2023

Status Verified

November 1, 2023

Enrollment Period

9.4 years

First QC Date

November 16, 2016

Last Update Submit

November 26, 2023

Conditions

Acute Kidney Injury

Keywords

Acute Kidney InjuryProteinosisEpidemiologyRisk factors

Outcome Measures

Primary Outcomes (1)

  • all-cause mortality

    90 days

Secondary Outcomes (2)

  • renal function survival rate

    90 days

  • days in hospital

    90 days

Study Arms (1)

Hospital-acquired AKI

Adult patients with Hospital-acquired AKI

Eligibility Criteria

Age18 Years - 89 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

adult patients aged \>18 years, with hospital-acquired acute kidney injury, from a university-affiliated hospital in Shanghai, China.

You may qualify if:

  • age \>=18 years and \<= 88 years
  • clinically diagnosed with acute kidney injury, according KDIGO criteria.

You may not qualify if:

  • preexisting chronic kidney failure (defined as an eGFR \<60 ml/min per 1.73 m2)
  • post-renal obstruction or rapid progressive glomerulonephritis as the main cause of AKI
  • known acute renal dysfunction
  • hospital stays \<24 hours
  • malignancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Ninth People's Hospital

Shanghai, Shanghai Municipality, 200011, China

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

blood or urine samples

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Officials

  • Feng Ding, PhD

    Division of Nephrology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University

    STUDY DIRECTOR

Central Study Contacts

Feng Ding, PhD

CONTACT

86-21-53315165dingfeng@sjtu.edu.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

November 16, 2016

First Posted

November 18, 2016

Study Start

January 1, 2015

Primary Completion

June 1, 2024

Study Completion

June 1, 2024

Last Updated

November 28, 2023

Record last verified: 2023-11

Locations

CN(1)