Clinical Values of Automated Electronic Alert for Acute Kidney Injury
1 other identifier
interventional
2,000
1 country
1
Brief Summary
Acute kidney injury (AKI) is common, serious and expensive.It is associated with significant mortality, morbidity and increased length of hospital stay.To improve clinical outcomes of AKI by early detection and timely referral to the renal,the investigators developed an electronic alert system which identifies all cases of AKI occurring in patients over 18 years.The system was also designed to collect data on AKI incidence one of the biggest tertiary hospital in China.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2016
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2016
CompletedFirst Submitted
Initial submission to the registry
May 23, 2016
CompletedFirst Posted
Study publicly available on registry
June 8, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2022
CompletedFebruary 23, 2023
February 1, 2023
5.8 years
May 23, 2016
February 21, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Adverse events during hospitalization
cardiac shock/ need for intensive care/ cardiopulmonary resuscitation/ cardiac death/ death
from start of AKI to discharge,up to 4 weeks
Incidence of cardiovascular disease and its occurrence time followed up for 1 years
heart failure/ acute coronary syndrome/ readmission/cardiac readmission/ cardiovascular intervention or surgery
One year after discharge
The AKI outcome and its occurrence time followed up for 1 years
AKI recovery/stop renal replacement therapy
One year after discharge
AKI recovery/stop renal replacement therapy
Glomerular filtration rate decreased/ new occurrence proteinuria/ original proteinuria aggravation
from start of AKI to discharge,up to 4 weeks
Secondary Outcomes (3)
Proportion of nephrology referral
from start of AKI to discharge,up to 4 weeks
Diagnostic rate of AKI at discharge
from start of AKI to discharge,up to 4 weeks
Follow-up rate after discharge
One year after discharge
Study Arms (2)
Usual care
NO INTERVENTIONpatients will receive standard clinical care by the doctor in charge.
AKI alert
EXPERIMENTALan AKI alert will send to the the doctor in charge.Our team of nephrologists would give suggestions if the doctor in charge issue consultation application.
Interventions
Eligibility Criteria
You may qualify if:
- adult patients with an Alert for AKI(based on KDIGO guidelines)
You may not qualify if:
- patients already on dialysis for AKI at the time of alert
- patients with End stage renal disease
- patients \<18 years of age
- patients dissenting from participation according to the Ethics application
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- XinLing Lianglead
Study Sites (1)
Nephrology Dept,Guangdong General Hospital
Guangzhou, Guangdong, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Director of Blood Purification Center of Guangdong General Hospital
Study Record Dates
First Submitted
May 23, 2016
First Posted
June 8, 2016
Study Start
March 1, 2016
Primary Completion
December 1, 2021
Study Completion
June 1, 2022
Last Updated
February 23, 2023
Record last verified: 2023-02