NCT03061786

Brief Summary

Acute kidney injury (AKI) is a common clinical syndrome, especially in the hospital patients. AKI is recognized as an important risk factor for incident chronic kidney disease, accelerated progression to end-stage renal disease,and increased risk of short-term and long-term mortality.This study is to observe the prognosis of hospitalized patients with AKI in China.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jan 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 15, 2017

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 23, 2017

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

May 12, 2026

Status Verified

May 1, 2026

Enrollment Period

2.9 years

First QC Date

February 15, 2017

Last Update Submit

May 7, 2026

Conditions

Acute Kidney Injury

Outcome Measures

Primary Outcomes (4)

  • estimated glomerular filtration rate decline

    \>50% baseline

    2 years

  • Chronic kidney disease classification upgrade

    2 years

  • New cardiovascular events

    2 years

  • All-cause mortality

    2 years

Secondary Outcomes (2)

  • AKI recovery

    2 years

  • Rehospitalization

    2 years

Study Arms (2)

AKI

non-AKI

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Hospitalized patients

You may qualify if:

  • clinically diagnosed with acute kidney injury, according to KDIGO criteria

You may not qualify if:

  • Nephrectomy
  • Kidney transplantation
  • Peak serum creatinine of less than 53µ mol/L
  • Serum creatinine decrease after amputation
  • Patients died during hospitalization
  • End-stage kidney disease(chronic kidney disease stage 5)
  • malnutrition

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guangdong General Hospital

Guangzhou, Guangdong, China

Location

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Director of Division of Nephrology and Blood Purification Center of Guangdong General Hospital

Study Record Dates

First Submitted

February 15, 2017

First Posted

February 23, 2017

Study Start

January 1, 2017

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

May 12, 2026

Record last verified: 2026-05

Locations

CN(1)