Phonological Treatment Paired With Intensive Speech Therapy Promotes Reading Recovery in Chronic Aphasia
1 other identifier
interventional
20
1 country
1
Brief Summary
Participants will receive either intensive phonology or semantic feature analysis treatment for 16 weeks to improve naming, reading, and writing in individuals with chronic post-stroke aphasia.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2015
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2015
CompletedFirst Submitted
Initial submission to the registry
February 17, 2016
CompletedFirst Posted
Study publicly available on registry
June 14, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2019
CompletedJuly 2, 2017
June 1, 2016
3.5 years
February 17, 2016
June 29, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Improvement in reading single words as measured by PALPA
Reading of single words will be testing using Psycholinguistic Assessment of Language Processing (PALPA) subtests
16 weeks
Improvement in naming as measured by BNT
picture naming (nouns) will be tested using Boston Naming Test (BNT)
16 weeks
Secondary Outcomes (1)
Improvement in spontaneous speech measured by WAB
16 weeks
Study Arms (2)
Intensive Phonology Treatment
EXPERIMENTALThe participants in the experimental group will receive an hour of phonology treatment, an hour of group therapy, and an hour of reading. They will work on writing, generative naming during group time focusing on self-cueing with the sounds they learn during the individual session. They will be read to or read aloud depending on their level. The participants in the experimental group will be taught all consonants and vowels over the course of 16 weeks.
Intensive SFA Treatment
ACTIVE COMPARATORThe participants in the control group will receive an hour of individual therapy, an hour of reading and an hour of group therapy in a traditional setting. They will work on writing, generative naming during group time following the semantic feature analysis to retrieve the name.They will be read to or read aloud depending on their level.
Interventions
Phonology based reading, writing, and naming therapy.
Semantic based reading, writing, and naming therapy.
Eligibility Criteria
You may qualify if:
- Male or female
- years old
- Have suffered a left CVA
- Score above 50% on comprehension task of the WAB
- Score below 80% accuracy on all phonology related tasks
You may not qualify if:
- Score above 80% accuracy on all phonology related tasks.
- Score below 50% on comprehension task of the WAB
- Have suffered a right CVA
- Are receiving teletherapy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Austin Speech Labs
Austin, Texas, 78757, United States
Related Publications (8)
Beeson PM, Rising K, Kim ES, Rapcsak SZ. A treatment sequence for phonological alexia/agraphia. J Speech Lang Hear Res. 2010 Apr;53(2):450-68. doi: 10.1044/1092-4388(2009/08-0229).
PMID: 20360466BACKGROUNDBrookshire CE, Conway T, Pompon RH, Oelke M, Kendall DL. Effects of intensive phonomotor treatment on reading in eight individuals with aphasia and phonological alexia. Am J Speech Lang Pathol. 2014 May;23(2):S300-11. doi: 10.1044/2014_AJSLP-13-0083.
PMID: 24686537BACKGROUNDCarlomagno S, Pandolfi M, Labruna L, Colombo A, Razzano C. Recovery from moderate aphasia in the first year poststroke: effect of type of therapy. Arch Phys Med Rehabil. 2001 Aug;82(8):1073-80. doi: 10.1053/apmr.2001.25155.
PMID: 11494187BACKGROUNDConway TW, Heilman P, Rothi LJ, Alexander AW, Adair J, Crosson BA, Heilman KM. Treatment of a case of phonological alexia with agraphia using the Auditory Discrimination in Depth (ADD) program. J Int Neuropsychol Soc. 1998 Nov;4(6):608-20. doi: 10.1017/s1355617798466104.
PMID: 10050366BACKGROUNDDoesborgh SJ, van de Sandt-Koenderman MW, Dippel DW, van Harskamp F, Koudstaal PJ, Visch-Brink EG. Effects of semantic treatment on verbal communication and linguistic processing in aphasia after stroke: a randomized controlled trial. Stroke. 2004 Jan;35(1):141-6. doi: 10.1161/01.STR.0000105460.52928.A6. Epub 2003 Dec 4.
PMID: 14657447BACKGROUNDEl Hachioui H, Lingsma HF, van de Sandt-Koenderman ME, Dippel DW, Koudstaal PJ, Visch-Brink EG. Recovery of aphasia after stroke: a 1-year follow-up study. J Neurol. 2013 Jan;260(1):166-71. doi: 10.1007/s00415-012-6607-2. Epub 2012 Jul 22.
PMID: 22820721BACKGROUNDGoodglass H, Wingfield A, Hyde MR, Gleason JB, Bowles NL, Gallagher RE. The importance of word-initial phonology: error patterns in prolonged naming efforts by aphasic patients. J Int Neuropsychol Soc. 1997 Mar;3(2):128-38.
PMID: 9126854BACKGROUNDGreenwald M. "Blocking" lexical competitors in severe global agraphia: a treatment of reading and spelling. Neurocase. 2004 Apr;10(2):156-74. doi: 10.1080/13554790409609946.
PMID: 15788254BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Shilpa Shamapant, M.S.,M.A.
Austin Speech Labs
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, CARE PROVIDER
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 17, 2016
First Posted
June 14, 2016
Study Start
June 1, 2015
Primary Completion
December 1, 2018
Study Completion
June 1, 2019
Last Updated
July 2, 2017
Record last verified: 2016-06
Data Sharing
- IPD Sharing
- Will share