BEYOND Weight Loss Maintenance Study
Comparison of Two Weight Loss Maintenance Interventions in Counterweight Plus
1 other identifier
interventional
63
1 country
3
Brief Summary
A study to determine the effectiveness of two weight loss maintenance interventions in Counterweight Plus, a structured weight management programme.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable obesity
Started Apr 2016
Typical duration for not_applicable obesity
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 9, 2016
CompletedFirst Posted
Study publicly available on registry
February 17, 2016
CompletedStudy Start
First participant enrolled
April 12, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 22, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
November 22, 2019
CompletedApril 28, 2021
April 1, 2021
3.6 years
February 9, 2016
April 27, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Weight change
Difference between the two groups in change in body weight (kg)
Baseline, 26 weeks
Secondary Outcomes (6)
Weight change
Baseline, 52 weeks, 78 weeks
Acceptability
Baseline, 26 weeks, 52 weeks, 78 weeks
Behavioural strategies
78 weeks
Eating behaviours
Baseline, 26 weeks, 52 weeks, 78 weeks
Quality of life
Baseline, 26 weeks, 52 weeks, 78 weeks
- +1 more secondary outcomes
Study Arms (2)
Continuous energy restriction
ACTIVE COMPARATOR1 x formula food (202-209kcal) meal replacement per day
Intermittent energy restriction
EXPERIMENTAL4 x formula food (202-209kcal) total diet replacement per day, on 2 days per week
Interventions
1 x formula food (202-209kcal) meal replacement per day
4 x formula food (202-209kcal) total diet replacement per day, on 2 days per week
Eligibility Criteria
You may qualify if:
- Completed Counterweight Plus Total Diet Replacement and Food Reintroduction stages and achieved \>10kg weight loss
You may not qualify if:
- People currently participating in another clinical research trial (not including BEYOND Weight Loss study)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- NHS Greater Glasgow and Clydelead
- University of Glasgowcollaborator
Study Sites (3)
NHS Lothian
Edinburgh, United Kingdom
NHS Greater Glasgow and Clyde
Glasgow, United Kingdom
NHS Highland
Inverness, United Kingdom
Related Publications (1)
Brosnahan N, Hankey C, Leeds A, Leslie W, Thom G, Hutchison L, Govan L, Ross H, Lean MEJ. Diet strategies for maintaining substantial therapeutic weight loss: 78-week mixed methods randomised trial. Clin Nutr. 2025 Oct;53:188-198. doi: 10.1016/j.clnu.2025.08.009. Epub 2025 Aug 12.
PMID: 40934815DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Michael Lean, FRCPS
University of Glasgow
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 9, 2016
First Posted
February 17, 2016
Study Start
April 12, 2016
Primary Completion
November 22, 2019
Study Completion
November 22, 2019
Last Updated
April 28, 2021
Record last verified: 2021-04