Peer Support for Weight Loss Maintenance
2 other identifiers
interventional
849
1 country
2
Brief Summary
The primary aim of this study is to test the efficacy of patient-provided treatment for weight-loss maintenance.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable obesity
Started Feb 2018
Longer than P75 for not_applicable obesity
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 29, 2017
CompletedFirst Posted
Study publicly available on registry
January 11, 2018
CompletedStudy Start
First participant enrolled
February 19, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 16, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
March 21, 2023
CompletedResults Posted
Study results publicly available
May 2, 2024
CompletedJune 12, 2024
May 1, 2024
5.1 years
December 29, 2017
April 9, 2024
May 16, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Weight Change (kg)
Weight change (measured on a digital scale to the nearest 0.1-kilogram) from Phase II Baseline (post-Phase I) to the end of the Phase II maintenance program (18 months).
Baseline to 18-months
Secondary Outcomes (1)
Blood Pressure (mmHg)
Baseline to 18-months
Study Arms (2)
Peer-Delivered Weight Maintenance
ACTIVE COMPARATORContingent upon participants losing 5% of body weight or more in Phase I (weight loss) of this trial, participants will receive an 18-month patient-delivered behavioral weight maintenance intervention. Specifically, group sessions will be delivered by a mentor (i.e., successful weight loser) and weekly coaching will be delivered by a peer (other member of their weight maintenance group).
Professionally-Delivered Weight Maintenance
ACTIVE COMPARATORContingent upon participants losing 5% of body weight or more in Phase I (weight loss) of this trial, participants will receive an 18-month reduced intensity behavioral weight maintenance intervention, delivered by a professional. The intervention will consist of 24 group sessions.
Interventions
Contingent upon participants losing 5% of body weight or more in Phase I (weight loss) of this trial, participants will receive an 18-month patient-delivered behavioral weight maintenance intervention. Specifically, group sessions will be delivered by a mentor (i.e., successful weight loser) and weekly coaching will be delivered by a peer (other member of their weight maintenance group).
Contingent upon participants losing 5% of body weight or more in Phase I (weight loss) of this trial, participants will receive an 18-month reduced intensity behavioral weight maintenance intervention, delivered by a professional. The intervention will consist of 24 group sessions.
Eligibility Criteria
You may qualify if:
- Age between 18-75
- Body Mass Index between 25-50
- English Speaking
You may not qualify if:
- Report being unable to walk 2 blocks without stopping
- Are currently participating in weight loss treatment, have a history of bariatric surgery, or lost ≥5% in the past 6-months
- Are pregnant or plan to become pregnant within 1 year
- Report a heart condition, chest pain during periods of rest or activity, or loss of consciousness on the Physical Activity Readiness Questionnaire
- Report a medical condition that could jeopardize their safety in a weight control program with diet and exercise guidelines
- Report conditions that, in the judgment of the PI, would render them unlikely to follow the protocol (e.g., relocation, dementia, unable to read and write in English)
- Have no Internet access.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Connecticutlead
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)collaborator
- Stanford Universitycollaborator
- The Miriam Hospitalcollaborator
Study Sites (2)
UConn's Weight Management Research Group
Hartford, Connecticut, 06103, United States
Institute for Collaboration on Health, Intervention and Policy
Storrs, Connecticut, 06269, United States
Related Publications (1)
Leahey TM, Gorin AA, Huedo-Medina TB, Denmat Z, Field C, Gilder C, Wyckoff EP, O'Connor K, Hahn K, Jenkins K, Unick JL, Hand G, McManus-Shipp K, Calcaterra J, Falk G. Patient-Delivered Continuous Care for Weight Loss Maintenance: A Randomized Clinical Trial. JAMA Intern Med. 2025 Jul 1;185(7):767-776. doi: 10.1001/jamainternmed.2025.1345.
PMID: 40423949DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Zeely Denmat
- Organization
- University of Connecticut
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
December 29, 2017
First Posted
January 11, 2018
Study Start
February 19, 2018
Primary Completion
March 16, 2023
Study Completion
March 21, 2023
Last Updated
June 12, 2024
Results First Posted
May 2, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will not share