Green Tea Attenuates Pressure Reduction Induced by a Session of Physical Exercise

NCT02578927 | Completed DMC

• 1 other identifier: FUParaíba
• Study Type: interventional
• Target: 15
• Locations: 0 countries
• Sites: N/A

Brief Summary

The objective is to investigate whether the ingestion of green tea prior to physical exercise improvement post-exercise hypotension (PEH). Double-blind, randomized, placebo study. Fifteen hypertensive (53±4.5 years) performed three procedures: green tea+exercise (GT+Ex), placebo+exercise (PL+Ex), green tea without exercise (GT). Thirty minutes after ingesting 2g of green tea or placebo, they performed treadmill walking (60 minutes), 60 to 85% of maximum heart rate intensity in procedures with exercises. BP was measured at rest and at every 10 minutes after exercise (60 minutes). Blood samples were taken before the ingestion of green tea or placebo and immediately after exercise to determine Malondialdehyde (MDA) and Nitrite (NO) dosages. Reduction of systolic BP compared with the rest, during PL+Ex recovery procedure.

Conditions

Hypertension

Outcome Measures

Primary Outcomes (1)

• Blood Pressure

  The sessions of exercise were released with interval of 30 days between them, thus each volunteer devoted an average 40 days to the study.

  Change from baseline Bood Pressure at 60 minutes post exercise in the same experimental session

Study Arms (3)

GT+Ex

EXPERIMENTAL

Ingestion of one dose of 2 g of green tea (GT) ingested at 10 minutes after the period of rest. After the Ingestion, the volunteers practice aerobic exercise (EX) in treadmill.

Dietary Supplement: GT+Ex

PL+Ex

PLACEBO COMPARATOR

Ingestion of one dose 2 g of placebo (PL) ingested at 10 minutes after the period of rest. After the Ingestion, the volunteers practice aerobic exercise (EX) in treadmill.

Dietary Supplement: PL+Ex

Green Tea

ACTIVE COMPARATOR

Ingestion of one dose 2g of green tea (GT) at 10 minutes after the period of rest. In this section the volunteers does not practice aerobic exercise.

Dietary Supplement: Green Tea

Interventions

GT+Ex DIETARY_SUPPLEMENT

In this session the volunteers ingested capsules with 2g of powder green tea before exercise

GT+Ex

PL+Ex DIETARY_SUPPLEMENT

In this session the volunteers ingested capsules with 2g of placebo before exercise

PL+Ex

Green Tea DIETARY_SUPPLEMENT

In this investigation the volunteers ingested capsules with 2g of powder green tea before the rest similar to the exercise time

Green Tea

Eligibility Criteria

• Age: 40 Years - 59 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Hypertensive
• Physically active for at least 3 months
• Not diabetics individuals.

You may not qualify if:

• Modifying the therapeutic treatment during the study
• Use beta-blocker drugs, and calcium channel blockers
• Menopausal women.

Sponsors & Collaborators

• Federal University of Paraíba: lead

MeSH Terms

Conditions

Hypertension

Interventions

Tea

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Plant Preparations; Biological Products; Complex Mixtures; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Manoel Miranda Neto, graduation

  Federal University of Paraíba

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Graduate

Study Record Dates

• First Submitted: September 11, 2015
• First Posted: October 19, 2015
• Study Start: January 1, 2013
• Primary Completion: June 1, 2015
• Study Completion: June 1, 2015
• Last Updated: October 19, 2015

Record last verified: 2015-10